Evidence map›Paper›PMID 35565298›Full record

ArticleCancers2022

Arginine Methyltransferase PRMT7 Deregulates Expression of RUNX1 Target Genes in T-Cell Acute Lymphoblastic Leukemia.

Laura Oksa, Artturi Mäkinen, Atte Nikkilä, Noora Hyvärinen, Saara Laukkanen, Anne Rokka, Pekka Haapaniemi, Masafumi Seki, Junko Takita, Otto Kauko and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Laura OksaTampere Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, FI-33520 Tampere, Finland.ORCID 0000-0003-4468-9877
Artturi MäkinenTampere Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, FI-33520 Tampere, Finland.ORCID 0000-0002-5521-9216
Atte NikkiläTampere Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, FI-33520 Tampere, Finland.ORCID 0000-0003-0292-2386
Noora HyvärinenTampere Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, FI-33520 Tampere, Finland.
Saara LaukkanenTampere Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, FI-33520 Tampere, Finland.ORCID 0000-0001-6328-1741
Anne RokkaTurku Bioscience Center, University of Turku and Åbo Akademi University, FI-20014 Turku, Finland.
Pekka HaapaniemiTurku Bioscience Center, University of Turku and Åbo Akademi University, FI-20014 Turku, Finland.
Masafumi SekiDepartment of Cell and Molecular Biology, Karolinska Institutet, SE-17165 Solna, Sweden.
Junko TakitaGraduate School of Medicine, Kyoto University, Kyoto JP-606-8501, Japan.
Otto KaukoTurku Bioscience Center, University of Turku and Åbo Akademi University, FI-20014 Turku, Finland.
Merja HeinäniemiThe Institute of Biomedicine, University of Eastern Finland, FI-70211 Kuopio, Finland.
Olli LohiTampere Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, FI-33520 Tampere, Finland.ORCID 0000-0001-9195-0797
Tampere University · FIÅbo Akademi University · FIKarolinska Institutet · SEKyoto University · JPUniversity of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with no well-established prognostic biomarkers. We examined the expression of protein arginine methyltransferases across hematological malignancies and discovered high levels of

Indexed as

arginine methylationLeukemiaPRMT7RUNX1T-ALL

Identifiers

PMID35565298
PMCPMC9101393
OpenAlexW4224949063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.