Evidence map›Paper›PMID 35565271›Full record

ArticleCancers2022

Differences in the Active Endometrial Microbiota across Body Weight and Cancer in Humans and Mice.

Nadeem O Kaakoush, Ellen M Olzomer, Melidya Kosasih, Amy R Martin, Farokh Fargah, Neil Lambie, Daniella Susic, Kyle L Hoehn, Rhonda Farrell, Frances L Byrne

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. VaginalFrontiers in cellular and infection microbiology · 2026
    Article
  3. Article
  4. Article
  5. Reproductive tract microbiome dysbiosis associated with gynecological diseases.Frontiers in cellular and infection microbiology · 2025
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Nadeem O KaakoushSchool of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Ellen M OlzomerSchool of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney, NSW 2052, Australia.
Melidya KosasihSchool of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Amy R MartinSchool of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Farokh FargahLaverty Pathology-North Ryde, Macquarie Park, Sydney, NSW 2113, Australia.
Neil LambieDepartment of Anatomical Pathology, Canterbury Health Laboratories, Christchurch 8011, New Zealand.
Daniella SusicSchool of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Kyle L HoehnSchool of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-0214-3238
Rhonda FarrellChris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.ORCID 0000-0001-7036-8968
Frances L ByrneSchool of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-8897-8438
UNSW Sydney · AUCanterbury Health Laboratories · NZChris O’Brien Lifehouse · AURoyal North Shore Hospital · AU

Funding

Cancer Institute of New South Wales 2021/CDF1120 (FLB)Royal Australian and New Zealand College of Obstetricians and Gynecologists Mary Elizabeth Courier Research ScholarshipTranslational Cancer Research Network NAUNSW School of Biotechnology & Biomolecular Sciences Next Generation Sequencing grantUNSW Sydney Scientia fellowship (NOK)
6 · The paper itself

Abstract

Obesity is a risk factor for endometrial cancer. The aim of this study was to determine whether actively replicating microbiota in the endometrium differ between obese vs. lean and cancer vs. benign states. We performed 16S rRNA amplicon sequencing on endometrial tissues from lean and obese women with and without endometrial cancer, and lean and obese mice. Results displayed human endometrial microbiota clustered into three community types (R = 0.363,

Indexed as

lactobacillusmicrobiotaobesityuterine cancer

Identifiers

PMID35565271
PMCPMC9100094
OpenAlexW4224433768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.