ArticleCancers2022
Functional Outcomes in Head and Neck Cancer Patients.
Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Prevalence and characteristics of persistent pain among head and neck cancer survivors: a systematic review and meta-analysis.Pain medicine (Malden, Mass.) · 2025Pooled it
- Rates and Outcomes of Head and Neck Cancer Among Patients With Primary Immunodeficiency Disorders.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Nano-silymarin combined with methylene blue photodynamic therapy versus monotherapies of head and neck squamous cell carcinoma: in-vitro study.BMC cancer · 2026Article
- Patient-Reported Outcomes and Functional Recovery After Treatment for Laryngeal Cancer: A Scoping Review of Instruments, Domains, and Clinical Integration.Journal of clinical medicine · 2026Review
- Review
- [Prevention in oncological follow-up].HNO · 2026Review
- Patient Satisfaction and Supportive Care Pathways in a German Head and Neck Tumor Center: A Prospective Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Long-term outcomes among individuals living with and beyond head and neck cancer: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Enhanced Antitumor Efficacy of a Combination of Immunotoxin and Photosensitizer Under Illumination in Xenograft Mice.Biomedicines · 2026Article
- Caregiver health literacy in head and neck cancer and its relationship with caregiver and patient psychological distress.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Specific Depressive Symptoms and Primary Tumor Location as Potential Predictors of Smoking Maintenance After Head and Neck Cancer Treatment.Psycho-oncology · 2026Article
- Unmet supportive care needs among head and neck cancer survivors in China: multicenter cross-sectional study.Frontiers in public health · 2026Article
- Incidence, severity, and risk factors of early postoperative complications in laryngectomy patients: a retrospective analysis.Discover oncology · 2025Article
- Psychometric validation of the Chinese version of the Edmonton-33 scale in patients with head and neck cancer.Asia-Pacific journal of oncology nursing · 2025Article
- Article
- Cancer-related pain in head and neck cancer survivors: longitudinal findings from the Head and Neck 5000 clinical cohort.Journal of cancer survivorship : research and practice · 2025Article
- Outcomes of Management of Advanced oral Cavity Carcinoma (T3 and T4) Following Surgery and Chemoradiotherapy Among Rural Population in Gujarat.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Evaluating Effective Feeding Methods for Nutritional Management in Head and Neck Cancer Patients Post-Surgery: A Systematic Review.ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses · 2025Article
- Individualized home training in head and neck cancer patients is safe and has positive short- and medium-term effects -results of a multicenter, single-arm intervention trial (OSHO #94).Frontiers in oncology · 2025Article
- Surgical learning curve and flap survival in head and neck microvascular reconstruction using arterial and venous couplers.Contemporary oncology (Poznan, Poland) · 2025Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the increase in long-term survivorship of head and neck cancer (HNC), the functional outcomes are gaining importance. We reported the functional outcomes of HNC patients using the HNC-Functional InTegrity (FIT) Scales, which is a validated tool for the rapid clinical assessment of functional status based on observable clinical criteria. Patients with newly diagnosed HNC treated at the Medical University of Innsbruck between 2008 and 2020 were consecutively included, and their status in the six functional domains of food-intake, breathing, speech, pain, mood, and neck and shoulder mobility was scored by the treating physician at oncological follow-up visits on a scale from 0 (loss of function) to 4 (full function). HNC-FIT scales were available for 681 HNC patients at a median of 35 months after diagnosis. The response status was complete remission in 79.5%, 18.1% had recurrent or persistent disease, and 2.4% had a second primary HNC. Normal or near-normal scores (3 and 4) were seen in 78.6% for food intake, 88.7% for breathing, 83.7% for speech, 89% for pain, 91.8% for mood, and 87.5% for neck and shoulder mobility. A normal or near-normal outcome in all six functional domains was observed in 61% of patients. Clinically relevant impairment (score 1-2) in at least one functional domain was observed in 30%, and 9% had loss of function (score 0) in at least one functional domain. The main factors associated with poor functional outcome in a multivariable analysis were recurrence or persistent disease, poor general health (ASA III and IV), and higher T stage. Particularly, laryngeal and hypopharyngeal tumors impaired breathing and speech function, and primary radiation therapy or concomitant systemic therapy and radiotherapy worsened food intake. Clinically relevant persistent functional deficits in at least one functional domain must be expected in 40% of the patients with HNC. The treatment of these functional deficits is an essential task of oncologic follow-up.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.