Evidence map›Paper›PMID 35565189›Full record

ReviewCancers2022

Current and Developing Liquid Biopsy Techniques for Breast Cancer.

Hsing-Ju Wu, Pei-Yi Chu

Abstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
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  10. microRNAs as Biomarkers of Breast Cancer.International journal of molecular sciences · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hsing-Ju WuResearch Assistant Center, Show Chwan Memorial Hospital, Changhua 500, Taiwan.ORCID 0000-0002-2005-495X
Pei-Yi ChuDepartment of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0001-7336-2465

Funding

Ministry of Science and Technology MOST 106-2314-B-442-001-MY3Ministry of Science and Technology MOST 109-2314-B-075B-002Ministry of Science and Technology MOST 109-2314-B-442-001National Health Research Institutes NHRI-109BCCO-MF-202015-01Show Chwan Memorial Hospital RD-107063Show Chwan Memorial Hospital SRD-109023Show Chwan Memorial Hospital SRD-109035Show Chwan Memorial Hospital SRD-110052
6 · The paper itself

Abstract

Breast cancer is the most commonly diagnosed cancer and leading cause of cancer mortality among woman worldwide. The techniques of diagnosis, prognosis, and therapy monitoring of breast cancer are critical. Current diagnostic techniques are mammography and tissue biopsy; however, they have limitations. With the development of novel techniques, such as personalized medicine and genetic profiling, liquid biopsy is emerging as the less invasive tool for diagnosing and monitoring breast cancer. Liquid biopsy is performed by sampling biofluids and extracting tumor components, such as circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), cell-free mRNA (cfRNA) and microRNA (miRNA), proteins, and extracellular vehicles (EVs). In this review, we summarize and focus on the recent discoveries of tumor components and biomarkers applied in liquid biopsy and novel development of detection techniques, such as surface-enhanced Raman spectroscopy (SERS) and microfluidic devices.

Indexed as

breast cancercirculating tumor cellscirculating tumor DNAextracellular vesiclesliquid biopsymicroRNA

Identifiers

PMID35565189
PMCPMC9105073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.