Evidence map›Paper›PMID 35565057›Full record

ArticleInternational journal of environmental research and public health2022

Potential Biomarkers and Drugs for Nanoparticle-Induced Cytotoxicity in the Retina: Based on Regulation of Inflammatory and Apoptotic Genes.

Dongli Xie, Jianchen Hu, Tong Wu, Kangli Cao, Xiaogang Luo

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Retinal toxicity of heavy metals and its involvement in retinal pathology.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dongli XieCollege of Textile and Clothing Engineering, Soochow University, 199 Ren-Ai Road, Suzhou 215123, China.
Jianchen HuCollege of Textile and Clothing Engineering, Soochow University, 199 Ren-Ai Road, Suzhou 215123, China.
Tong WuShanghai Jing Rui Yang Industrial Co., Ltd., 3188 Xiupu Road, Pudong New Area, Shanghai 200122, China.
Kangli CaoShanghai Institute of Spacecraft Equipment, 251 Huaning Road, Shanghai 200240, China.
Xiaogang LuoCollege of Textile and Clothing Engineering, Soochow University, 199 Ren-Ai Road, Suzhou 215123, China.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The eye is a superficial organ directly exposed to the surrounding environment. Thus, the toxicity of nanoparticle (NP) pollutants to the eye may be potentially severer relative to inner organs and needs to be monitored. However, the cytotoxic mechanisms of NPs on the eyes remain rarely reported. This study was to screen crucial genes associated with NPs-induced retinal injuries. The gene expression profiles in the retina induced by NPs [GSE49371: Au20, Au100, Si20, Si100; GSE49048: presumptive therapeutic concentration (PTC) TiO

Indexed as

MicroRNAsNanoparticlesOptic Nerve InjuriesRNA, Long NoncodingBiomarkersFolic AcidHumansHydrogen PeroxideHypoxiaInterferon Regulatory FactorsRetinaRNA, MessengerToll-Like Receptor 2BiomarkersFolic AcidHydrogen PeroxideInterferon Regulatory FactorsMicroRNAsRNA, Long NoncodingRNA, MessengerToll-Like Receptor 2apoptosiscompeting endogenous RNAsinflammationlong non-coding RNAsnanoparticlesretinal injury

Identifiers

PMID35565057
PMCPMC9099825
OpenAlexW4229034478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.