Evidence map›Paper›PMID 35565022›Full record

ArticleInternational journal of environmental research and public health2022

Nano-Hydroxyapatite (nHAp) in the Remineralization of Early Dental Caries: A Scoping Review.

Aiswarya Anil, Wael I Ibraheem, Abdullah A Meshni, Reghunathan S Preethanath, Sukumaran Anil

Open access · goldAbstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Aiswarya AnilSaveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 602105, India.
Wael I IbraheemCollege of Dentistry, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia.
Abdullah A MeshniCollege of Dentistry, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia.
Reghunathan S PreethanathCollege of Dentistry, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia.ORCID 0000-0002-6221-0578
Sukumaran AnilOral Health Institute, Department of Dentistry, Hamad Medical Corporation, Doha 3050, Qatar.ORCID 0000-0002-6440-8780
Jazan University · SAHamad Medical Corporation · QASaveetha University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Nano-hydroxyapatite (nHAp) has been reported to have a remineralizing effect on early carious lesions. The objective of this scoping review was to analyze the remineralization potential of nano-hydroxyapatite (nHAp)-containing dentifrices, by mapping the existing literature. (2) Methods: This review was performed using the PRISMA-ScR Checklist, which is an extension of the PRISMA Checklist for Systematic Reviews and Meta-Analyses. In this study, the population, concept, and context (PCC) framework was used to find relevant papers published between 2010 and 2021. Nano-hydroxyapatite (nHAp) and dentifrices containing nHAp as one of the ingredients were the two main concepts of the research question. MeSH phrases, keywords, and other free terms relevant to nano-hydroxyapatite and dentifrices were used to search the literature databases. (3) Results: Preliminary searches yielded 59 studies; the title and abstract screening results excluded 11 studies. The remaining studies were thoroughly reviewed by two reviewers on the basis of the inclusion and exclusion criteria. Finally, 28 studies were included, and 20 studies were excluded. Most of the studies that were included reported that when nHAp was used alone, it had many different effects, such as remineralization, caries prevention, less demineralization, brighter teeth, less pain, and remineralization of enamel after orthodontic debonding. (4) Conclusions: Dentifrices that contain nHAp offer a variety of therapeutic and preventative effects. Currently, there is insufficient evidence to support the efficacy of nHAp dentifrices in primary teeth. Additional long-term investigations using standardized protocols are required to reach decisive conclusions about the effects of nHAp dentifrices on primary and permanent dentitions.

Indexed as

Dental CariesDentifricesToothDurapatiteFluoridesHumansTooth RemineralizationDentifricesDurapatiteFluoridesdemineralizationdental cariesdentifricesnano-hydroxyapatiteremineralizationscoping review

Identifiers

PMID35565022
PMCPMC9102186
OpenAlexW4229009906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.