Evidence map›Paper›PMID 35564694›Full record

ReviewInternational journal of environmental research and public health2022

Delayed Neurological Sequelae Successfully Treated with Adjuvant, Prolonged Hyperbaric Oxygen Therapy: Review and Case Report.

Luca Martani, Andrea Giovanniello, Gerardo Bosco, Luca Cantadori, Francesca Calissi, Dany Furfaro, Massimo Pedrazzini, Rosanna Vaschetto, Enrico Mario Camporesi, Matteo Paganini

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Luca MartaniVaio Hospital, 43036 Fidenza, Italy.
Andrea GiovannielloCasa di Cura HABILITA I Cedri, 28073 Fara Novarese, Italy.
Gerardo BoscoDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0001-6595-7944
Luca CantadoriVaio Hospital, 43036 Fidenza, Italy.
Francesca CalissiRivoli Hospital, 10098 Rivoli, Italy.ORCID 0000-0001-9168-4513
Dany FurfaroOspedale Parini, 11100 Aosta, Italy.
Massimo PedrazziniVaio Hospital, 43036 Fidenza, Italy.
Rosanna VaschettoDepartment of Translational Sciences, University of Eastern Piedmont, 28100 Novara, Italy.ORCID 0000-0003-4625-4367
Enrico Mario CamporesiDepartment of Surgery, University of South Florida, Tampa, FL 33606, USA.
Matteo PaganiniDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-7556-6928
CTO Hospital · ITUniversity of Padua · ITOspedale di Rivoli · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon Monoxide (CO) intoxication is still a leading cause of mortality and morbidity in many countries. Due to the problematic detection in the environment and subtle symptoms, CO intoxication usually goes unrecognized, and both normobaric and hyperbaric oxygen (HBO) treatments are frequently administered with delay. Current knowledge is mainly focused on acute intoxication, while Delayed Neurological Sequelae (DNS) are neglected, especially their treatment. This work details the cases of two patients presenting a few weeks after CO intoxication with severe neurological impairment and a characteristic diffused demyelination at the brain magnetic resonance imaging, posing the diagnosis of DNS. After prolonged treatment with hyperbaric oxygen, combined with intravenous corticosteroids and rehabilitation, the clinical and radiological features of DNS disappeared, and the patients' neurological status returned to normal. Such rare cases should reinforce a thorough clinical follow-up for CO intoxication victims and promote high-quality studies.

Indexed as

Carbon Monoxide PoisoningHyperbaric OxygenationDisease ProgressionHumansOxygenOxygen Inhalation TherapyOxygencarbon monoxidedelayed neurologic sequelaehyperbaric oxygenhyperbaric oxygen therapyintoxicationpoisoning

Identifiers

PMID35564694
PMCPMC9104642
OpenAlexW4280491264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.