Evidence map›Paper›PMID 35564690›Full record

ArticleInternational journal of environmental research and public health2022

A Cross-Sectional Study of Ocular Changes in Children and Adolescents with Diabetes Mellitus in Selected Health Facilities in Ghana.

Vera A Essuman, Naa N Tagoe, Akye Essuman, Benjamin Abaidoo, Josephine Akpalu, Harold A Sackey, Charles F Hayfron-Benjamin, George Asare, Albert G B Amoah, Thomas A Ndanu and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Meta-Analysis of the Effect of Nursing Intervention on Children with Type 2 Diabetes.Computational and mathematical methods in medicine · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Promoting Health for Adolescents: An Editorial.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Vera A EssumanOphthalmology Unit, Department of Surgery, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.ORCID 0000-0001-8529-6362
Naa N TagoeEye Department, Korle Bu Teaching Hospital, Accra P.O. Box 77, Ghana.ORCID 0000-0001-5409-9884
Akye EssumanDepartment of Community Health, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.ORCID 0000-0002-0784-1123
Benjamin AbaidooOphthalmology Unit, Department of Surgery, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
Josephine AkpaluDepartment of Medicine and Therapeutics, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
Harold A SackeyDepartment of Child Health, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
Charles F Hayfron-BenjaminDepartment of Physiology, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
George AsareChemical Pathology Unit, Department of Medical Laboratory Sciences, University of Ghana School of Basic and Allied Health Sciences, College of Health Sciences, Accra P.O. Box GP 4236, Ghana.
Albert G B AmoahDepartment of Medicine and Therapeutics, University of Ghana Medical School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
Thomas A NdanuDepartment of Preventive & Community Dentistry, University of Ghana Dental School, University of Ghana, Accra P.O. Box GP 4236, Ghana.
Imelda D B Ofori-AdjeiEye Department, Korle Bu Teaching Hospital, Accra P.O. Box 77, Ghana.
Nana A BarnesSanta Rosa Community Health, Vista Clinic 3569 Round Barn Circle, Santa Rosa, CA 95403, USA.
Benedicta L Appiah-ThompsonEye Department, Cape-Coast Teaching Hospital, Cape Coast CT 1363, Ghana.
Winfried M AmoakuOphthalmology and Visual Sciences (DCN), University Hospital, QMC Nottingham, Nottingham NG7 2UH, UK.ORCID 0000-0001-5028-7984
University of Ghana · GHKorle Bu Teaching Hospital · GHUniversity of Cape Coast · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe main objective of the study was to determine the prevalence of diabetic retinopathy (DR), other diabetes-related ocular changes (e.g., cataracts, corneal ulceration), and non-diabetic ocular disease in Ghanaian children and adolescents. The second objective was to evaluate the relationship between these conditions and age at diagnosis, current age, diabetes mellitus (DM) duration, and participant's sex.

methodsA cross-sectional study, undertaken by a multidisciplinary team, included a cohort of children and adolescents (4-19 years) with DM recruited from selected health facilities in Ghana, from March 2016 to September 2019, after written informed consent or assent. The cohort will be followed up for 3 years to determine the natural course of the ocular changes, reported later. Participants were examined for all microvascular and macrovascular complications, non-diabetic ocular disease, anthropometric measurements, laboratory characteristics and quality of life issues. Full ocular examination was also undertaken. Statistical Package for Social Sciences (SPSS Version 25.0) was used for the data analysis. Continuous and categorical variables were presented as mean and standard deviation (SD), median (interquartile range) and as percentages (%), respectively. T-test and Mann-Whitney U test were used in establishing associations.

resultsA total of 58 participants were recruited. DR was detected in only 1 out of 58 (1.7%) participants at baseline. Cataracts were the most common ocular finding, detected in 42 (72%) at baseline. Other anterior segment changes observed included blepharitis 46 (79.3%) and tear film instability 38 (65.5%). There was a significant positive association between duration of the DM and the risk of cataract (

conclusionsDR was uncommon in this cohort of young persons with DM in Ghana. Cataracts, blepharitis and refractive errors were ocular changes commonly observed. All young persons with diabetes should undergo regular eye examination in all clinics where follow-up care is provided.

Indexed as

BlepharitisCataractDiabetes Mellitus, Type 2Diabetic RetinopathyAdolescentChildCross-Sectional StudiesGhanaHealth FacilitiesHumansPrevalenceQuality of LifeRisk Factorsdiabetes mellitusmicrovascularocular complicationsretinopathy

Identifiers

PMID35564690
PMCPMC9104046
OpenAlexW4280495350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.