Evidence map›Paper›PMID 35564681›Full record

ReviewInternational journal of environmental research and public health2022

Platelet Rich Plasma in Gynecology-Discovering Undiscovered-Review.

Dominika Streit-Ciećkiewicz, Aleksandra Kołodyńska, Karolina Futyma-Gąbka, Magdalena Emilia Grzybowska, Jakub Gołacki, Konrad Futyma

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07306611 (Regenerative Treatment of Female Genital Atrophy), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07306611 phase1 / phase2completednot on this mapstarted 2024, after this paper: background citation

Regenerative Treatment of Female Genital Atrophy

TypeinterventionalSponsorAndreiaAntunesRan2024 to 2025Enrolled30ConditionsVulvo Vaginal AtrophyArmsMesotherapy with Autologous Platelet-Rich Plasma (PRP) to vulvovaginal area, Mesotherapy with saline solution, Platelet-Poor Plasma Gel
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Utilization and efficacy of platelet-rich plasma and platelet-rich fibrin in otolaryngology: a systematic evidence-based review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Review
  7. Platelet-rich Plasma: ACurrent drug research reviews · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management.Obstetrics and gynecology international · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dominika Streit-Ciećkiewicz2nd Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.
Aleksandra Kołodyńska2nd Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.ORCID 0000-0002-8422-5594
Karolina Futyma-GąbkaDepartment of Dental and Maxillofacial Radiology, Medical University of Lublin, ul. Chodźki 6, 20-093 Lublin, Poland.
Magdalena Emilia GrzybowskaDepartment of Gynecology, Gynecologic Oncology and Gynecologic Endocrinology, Medical University of Gdańsk, Smoluchowskiego 17, 80-214 Gdańsk, Poland.ORCID 0000-0002-5311-3450
Jakub Gołacki2nd Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.
Konrad Futyma2nd Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.ORCID 0000-0001-7864-666X
Medical University of Lublin · PLGdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regenerative medicine combines elements of tissue engineering and molecular biology aiming to support the regeneration and repair processes of damaged tissues, cells and organs. The most commonly used preparation in regenerative medicine is platelet rich plasma (PRP) containing numerous growth factors present in platelet granularities. This therapy is increasingly used in various fields of medicine. This article is a review of literature on the use of PRP in gynecology and obstetrics. There is no doubt that the released growth factors and proteins have a beneficial effect on wound healing and regeneration processes. So far, its widest application is in reproductive medicine, especially in cases of thin endometrium, Asherman's syndrome, or premature ovarian failure (POF) but also in wound healing and lower urinary tract symptoms (LUTS), such as urinary incontinence or recurrent genitourinary fistula auxiliary treatment. Further research is, however, needed to confirm the effectiveness and the possibility of its application in many other disorders.

Indexed as

GynecologyPlatelet-Rich PlasmaEndometriumFemaleHumansPregnancyRegenerative MedicineTissue EngineeringAsherman’s syndromeplatelet rich fibrinplatelet rich plasmapremature ovarian failureurogynecologyvesicovaginal fistula

Identifiers

PMID35564681
PMCPMC9100365
OpenAlexW4225015053

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.