Evidence map›Paper›PMID 35564312›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Self-Healing Thiolated Pillar[5]arene Films Containing Moxifloxacin Suppress the Development of Bacterial Biofilms.

Dmitriy N Shurpik, Yulia I Aleksandrova, Olga A Mostovaya, Viktoriya A Nazmutdinova, Regina E Tazieva, Fadis F Murzakhanov, Marat R Gafurov, Pavel V Zelenikhin, Evgenia V Subakaeva, Evgenia A Sokolova and 5 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dmitriy N ShurpikA.M.Butlerov Chemical Institute, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.ORCID 0000-0002-7914-6533
Yulia I AleksandrovaA.M.Butlerov Chemical Institute, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.
Olga A MostovayaA.M.Butlerov Chemical Institute, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.
Viktoriya A NazmutdinovaA.M.Butlerov Chemical Institute, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.
Regina E TazievaA.M.Butlerov Chemical Institute, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.
Fadis F MurzakhanovInstitute of Physics, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.ORCID 0000-0001-7601-6314
Marat R GafurovInstitute of Physics, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.ORCID 0000-0002-2179-2823
Pavel V ZelenikhinInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.ORCID 0000-0003-1971-1745
Evgenia V SubakaevaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.
Evgenia A SokolovaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.
Alexander V GerasimovA.M.Butlerov Chemical Institute, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.ORCID 0000-0003-4213-9724
Vadim V GorodovEnikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences (ISPM RAS), Profsoyuznaya, 70, 117393 Moscow, Russia.
Daut R IslamovLaboratory for Structural Analysis of Biomacromolecules, Kazan Scientific Center of Russian Academy of Sciences, Lobachevskogo, 2/31, 420111 Kazan, Russia.
Peter J CraggSchool of Applied Sciences, University of Brighton, Huxley Building, Brighton BN2 4GJ, UK.ORCID 0000-0002-6134-2093
Ivan I StoikovA.M.Butlerov Chemical Institute, Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russia.ORCID 0000-0002-3019-7866

Funding

Russian Science Foundation 20-73-00161
6 · The paper itself

Abstract

Polymer self-healing films containing fragments of pillar[5]arene were obtained for the first time using thiol/disulfide redox cross-linking. These films were characterized by thermogravimetric analysis and differential scanning calorimetry, FTIR spectroscopy, and electron microscopy. The films demonstrated the ability to self-heal through the action of atmospheric oxygen. Using UV-vis, 2D 1H-1H NOESY, and DOSY NMR spectroscopy, the pillar[5]arene was shown to form complexes with the antimicrobial drug moxifloxacin in a 2:1 composition (logK11 = 2.14 and logK12 = 6.20). Films containing moxifloxacin effectively reduced

Indexed as

antibacterial activityelectron spin resonancemoxifloxacin hydrochloridepillar[5]arenepolymer filmspolythiolsself-healing

Identifiers

PMID35564312
PMCPMC9102331

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.