Evidence map›Paper›PMID 35563944›Full record

ArticleFoods (Basel, Switzerland)2022

In Vitro Anti-Obesity Effect of Shenheling Extract (SHLE) Fermented with

Xian-Tao Yan, Wenmiao Zhang, Yanyan Zhang, Ziqi Zhang, Dawei Chen, Wenqiong Wang, Wenlong Ma, Hengxian Qu, Jian-Ya Qian, Ruixia Gu

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Fermentation withFood chemistry: X · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Food chemistry: X · 2024
    Article
  6. Review
  7. Article
  8. Effects of fermentedFrontiers in cellular and infection microbiology · 2024
    Article
  9. Major Active Metabolite Characteristics ofFoods (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xian-Tao YanCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225012, China.ORCID 0000-0002-7382-3513
Wenmiao ZhangCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225012, China.
Yanyan ZhangTesting Center of Yangzhou University, Yangzhou 225012, China.
Ziqi ZhangCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225012, China.
Dawei ChenCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225012, China.
Wenqiong WangCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225012, China.
Wenlong MaCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225012, China.
Hengxian QuCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225012, China.
Jian-Ya QianCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225012, China.
Ruixia GuCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225012, China.

Funding

Major Science and Technology Application Demonstration Program of Chengdu 2019-YF09-00055-SNNational Key Research and Development Program of China 2019YFF0217602National Natural Science Foundation of China 31972094Natural Science Foundation of Jiangsu Province BK20211325Natural Science Foundation of the Jiangsu Higher Education Institutions of China National 19KJA140004
6 · The paper itself

Abstract

Obesity is a common global problem. There are many fat-reducing herbal prescriptions in traditional Chinese medicine that have been proven to be safe and functional during long-term application. Microbial fermentation can improve the efficacy of herbal medicine and improve the unsavory flavor. In this study, Shenheling extract (SHLE) composed of six medicine food homology materials was used as the research object. The purpose of this study was to evaluate the effects of Lactobacillusfermentum grx08 fermentation on the antiobesity efficacy and flavor of SHLE. We found that L. fermentum grx08 grew well in SHLE. After 72 h of fermentation, the total polysaccharides, total flavonoids, total polyphenols and total saponins of SHLE decreased, but the lipase inhibitory activity and total antioxidant capacity (FRAP) were significantly increased (p < 0.01). There were no significant differences in the α-glucosidase inhibition rate and DPPH· clearance rate before or after fermentation (p > 0.05). In addition, the fermentation reduces the unpleasant flavors of SHLE such as bitterness and grassy and cassia flavors. This study demonstrates that SHLE fermented by L. fermentum grx08 improved some anti-obesity functions and improved the unpleasant flavor.

Indexed as

anti-obesityfermentLactobacillus fermentummedicine food homology

Identifiers

PMID35563944
PMCPMC9104015

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.