ReviewCells2022
The Relationship between Obesity and Pre-Eclampsia: Incidental Risks and Identification of Potential Biomarkers for Pre-Eclampsia.
Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Association of LEPTIN and other inflammatory markers with preeclampsia: A systematic review.Frontiers in pharmacology · 2022Pooled it
- Effects of multivitamin combined with magnesium sulfate versus magnesium sulfate alone on hemodynamics, coagulation, and maternal-infant outcomes in preeclampsia: a randomized controlled study.Journal of health, population, and nutrition · 2025Trial
- Association between antenatal care utilization, preeclampsia, and neonatal Apgar scores among postnatal women in Eswatini: an analytical cross-sectional study.BMC pregnancy and childbirth · 2026Article
- Maternal Obesity Doubles the Risk of Preeclampsia and Eclampsia: Post-COVID Changes in a Brazilian Cohort of 2.3 Million Hospitalizations.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Article
- Hypoalbuminemia as a severity predictor of preeclampsia in a multicenter study from Indonesia.Scientific reports · 2026Article
- Understanding Preeclampsia: Integrating Placental Dysfunction, Immune Dysregulation and microRNA-Mediated Epigenetic Regulation.International journal of molecular sciences · 2026Review
- Beyond the Scale: Effects of Maternal Obesity on Embryo Morphokinetics and IVF Outcomes.Journal of clinical medicine · 2026Article
- Interaction Between Maternal Obesity and Metabolic Dysfunction in Gestational Hypertension and Preeclampsia: A Prospective Birth Cohort Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Genetic associations of miR-145 (rs353291) and miR-143/145 (rs3733846) with preeclampsia risk: a case-control analysis in maternal and cord blood.Molecular biology reports · 2025Article
- Causal relationships between metabolic syndrome, plasma metabolites, and female reproductive diseases: insights from a two-step mendelian randomization approach.Nutrition & metabolism · 2025Article
- Association of Postpartum Cardiovascular Biomarkers with HIV Among Women with Recent Preeclampsia in Zambia.Maternal and child health journal · 2025Article
- Diet-induced obesity alters the ovarian chemical biotransformation and oxidative stress response proteins both basally and in response to 7,12-dimethylbenz[a]anthracene exposure.Toxicological sciences : an official journal of the Society of Toxicology · 2025Article
- A Review of Dietary and Lifestyle Management of Pre-Eclampsia and Postpartum Eclampsia.Preventive nutrition and food science · 2025Review
- Early age at menarche is associated with an increased risk of preeclampsia and adverse neonatal outcomes: a 6‑year retrospective study.Archives of gynecology and obstetrics · 2024Article
- Genetic Insights and Neonatal Outcomes in Preeclampsia and Eclampsia: A Detailed Analysis of the RS5707 Genotype.Diagnostics (Basel, Switzerland) · 2024Article
- Exploring the impact of maternal factors and dietary habits on human milk oligosaccharide composition in early breastfeeding among Mexican women.Scientific reports · 2024Article
- The Role of Obesity in the Development of Preeclampsia.Current hypertension reports · 2024Review
- Morfofunctional and Molecular Changes in Placenta and Peripheral Blood in Preeclampsia and Gestational Diabetes Mellitus.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2023Article
- Is There a Relationship between Adverse Pregnancy Outcomes and Future Development of Atherosclerosis?Biomedicines · 2023Review
- Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective study.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity has been steadily increasing over the past decade in the US and worldwide. Since 1975, the prevalence of obesity has increased by 2% per decade, unabated despite new and more stringent guidelines set by WHO, CDC, and other public health organizations. Likewise, maternal obesity has also increased worldwide over the past several years. In the United States, pre-pregnancy rates have increased proportionally across all racial groups. Obesity during pregnancy has been directly linked to obstetric complications including gestational diabetes, HTN, hematomas, pre-eclampsia, and congenital defects. In the particular case of pre-eclampsia, the incidence rate across the globe is 2.16%, but the condition accounts for 30% of maternal deaths, and a robust body of evidence underscored the relationship between obesity and pre-eclampsia. More recently, attention has focused on the identification of reliable biomarkers predictive of an elevated risk for pre-eclampsia. The aim of this literature review is to elucidate the relationship between obesity and these predictive biomarkers for future prediction and prevention of pre-eclampsia condition in women at risk.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.