Evidence map›Paper›PMID 35563821›Full record

ReviewCells2022

The Role of N

Finn Morgan Auld, Consolato M Sergi, Roger Leng, Fan Shen

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Translational pediatrics: reflections for the 21Translational pediatrics · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Finn Morgan AuldDepartment of Laboratory Medicine and Pathology, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Consolato M SergiDivision of Anatomical Pathology, Children's Hospital of Eastern Ontario (CHEO), Ottawa, ON K1H 8L1, Canada.ORCID 0000-0002-2779-7879
Roger LengDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2B7, Canada.ORCID 0000-0001-9652-4703
Fan ShenDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2B7, Canada.
University of Alberta · CAUniversity of Ottawa · CA

Funding

CIHR 232514
6 · The paper itself

Abstract

Hepatoblastoma (HB) is a rare primary malignancy of the developing fetal liver. Its course is profoundly influenced by genetics, in the context of sporadic mutation or genetic syndromes. Conventionally, subtypes of HB are histologically determined based on the tissue type that is recapitulated by the tumor and the direction of its differentiation. This classification is being reevaluated based on advances on molecular pathology. The therapeutic approach comprises surgical intervention, chemotherapy (in a neoadjuvant or post-operative capacity), and in some cases, liver transplantation. Although diagnostic modalities and treatment options are evolving, some patients experience complications, including relapse, metastatic spread, and suboptimal response to chemotherapy. As yet, there is no consistent framework with which such outcomes can be predicted. N

Indexed as

HepatoblastomaLiver NeoplasmsLiver TransplantationAdenosineHumansNeoplasm Recurrence, LocalAdenosineN-methyladenosinebeta-cateninhepatoblastomahepatoblastoma geneticsm6AmethyltransferaseN6-Methyladenosine

Identifiers

PMID35563821
PMCPMC9101889
OpenAlexW4225248749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.