Evidence map›Paper›PMID 35563813›Full record

ArticleCells2022

Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX.

Sarah K Schröder, Herdit M Schüler, Kamilla V Petersen, Cinzia Tesauro, Birgitta R Knudsen, Finn S Pedersen, Frederike Krus, Eva M Buhl, Elke Roeb, Martin Roderfeld and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Working with Immortalized Hepatic Stellate Cell Lines.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Sarah K SchröderInstitute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D-52074 Aachen, Germany.
Herdit M SchülerInstitute of Human Genetics, University Hospital of RWTH Aachen University, D-52074 Aachen, Germany.
Kamilla V PetersenDepartment of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus, Denmark.
Cinzia TesauroVPCIR Biosciences ApS., DK-8000 Aarhus, Denmark.ORCID 0000-0003-2986-9618
Birgitta R KnudsenDepartment of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus, Denmark.
Finn S PedersenDepartment of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus, Denmark.ORCID 0000-0003-0981-0221
Frederike KrusInstitute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D-52074 Aachen, Germany.
Eva M BuhlElectron Microscopy Facility, Institute of Pathology, RWTH Aachen University Hospital, D-52074 Aachen, Germany.ORCID 0000-0003-0627-9228
Elke RoebDepartment of Gastroenterology, Justus Liebig University, D-35392 Giessen, Germany.ORCID 0000-0001-5739-5400
Martin RoderfeldDepartment of Gastroenterology, Justus Liebig University, D-35392 Giessen, Germany.ORCID 0000-0002-3232-1277
Radovan BorojevicInstitute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro 21941-590, Brazil.ORCID 0000-0002-2393-7280
Jamie L AlmeidaNational Institute of Standards and Technology, Biosystems and Biomaterials Division, Gaithersburg, MD 20899, USA.
Ralf WeiskirchenInstitute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D-52074 Aachen, Germany.ORCID 0000-0003-3888-0931
Aarhus University · DKUniversitätsklinikum Aachen · DEJustus-Liebig-Universität Gießen · DERWTH Aachen University · DENational Institute of Standards and Technology · USUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The murine cell line GRX has been introduced as an experimental tool to study aspects of hepatic stellate cell biology. It was established from livers of C3H/HeN mice that were infected with cercariae of

Indexed as

Hepatic Stellate CellsKupffer CellsAnimalsLiverMiceMice, Inbred C3HVitamin AVitamin A3R principleauthenticationcell linecross-contaminationgenotypinghepatic stellate cellslivermyofibroblastsretinolSTR profiling

Identifiers

PMID35563813
PMCPMC9102025
OpenAlexW4225138530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.