Evidence map›Paper›PMID 35563805›Full record

Trial reportCells2022

A Phase II Study on the Effect of Taurisolo

Stefano Sanduzzi Zamparelli, Ludovica Capitelli, Nicola Coppola, Claudia Venditto, Ciro Santoro, Giuseppe Annunziata, Dario Bruzzese, Nunzia Cuomo, Ivan Gentile, Marialuisa Bocchino and 1 more

Abstract readClinical Trial, Phase IIMulticenter Study
In one paragraph

Trial report in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stefano Sanduzzi ZamparelliPneumology I and Respiratory Pathophysiology Unit, Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", A. Cardarelli Hospital, 80131 Naples, Italy.
Ludovica CapitelliPneumology I and Respiratory Pathophysiology Unit, Department of Clinical Medicine and Surgery, Section of Respiratory Disease, University Federico II, A. Cardarelli Hospital, 80131 Naples, Italy.
Nicola CoppolaInfectious Diseases Unit, Department of Mental Health and Public Medicine, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.ORCID 0000-0001-5897-4949
Claudia VendittoDepartment of Clinical Medicine and Surgery, Section of Respiratory Diseases, University Federico II, Azienda Ospedaliera dei Colli-Monaldi Hospital, 80131 Naples, Italy.
Ciro SantoroDepartment of Advanced Biomedical Sciences, University Federico II, 80131 Naples, Italy.
Giuseppe AnnunziataDepartment of Pharmacy, University Federico II, 80131 Naples, Italy.ORCID 0000-0002-1922-662X
Dario BruzzeseDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Nunzia CuomoMicrobiology and Virology Unit, Cotugno Hospital, 80131 Naples, Italy.
Ivan GentileDepartment of Clinical Medicine and Surgery-Infectious Diseases, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-5199-8451
Marialuisa BocchinoDepartment of Clinical Medicine and Surgery, Section of Respiratory Diseases, University Federico II, Azienda Ospedaliera dei Colli-Monaldi Hospital, 80131 Naples, Italy.
Alessandro Sanduzzi ZamparelliDepartment of Clinical Medicine and Surgery, Section of Respiratory Diseases, University Federico II, Azienda Ospedaliera dei Colli-Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0002-0977-2643

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolyphenols are the largest class of bioactive compounds in plants, which are synthesized as secondary metabolites. In the last few years, interesting studies have demonstrated the efficacy of polyphenols against coronavirus infections.

methodswe conducted a phase II multicentric clinical trial (TAEROVID-19) during the first wave of the COVID-19 pandemic in order to assess the safety and feasibility of Taurisolo

resultswe observed a rapid decline of symptoms and a low rate of intensive care in patients treated with Taurisolo

conclusionsThis is the first trial assessing the safety and feasibility of Taurisolo

Indexed as

COVID-19 Drug TreatmentAerosolsHumansPandemicsPolyphenolsSARS-CoV-2AerosolsPolyphenolsCOVID-19 pneumoniaICU accesspolyphenols

Identifiers

PMID35563805
PMCPMC9101184

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.