Evidence map›Paper›PMID 35563730›Full record

ArticleCells2022

TRPM2 Promotes Atherosclerotic Progression in a Mouse Model of Atherosclerosis.

Yunting Zhang, Fan Ying, Xiaoyu Tian, Zhenchuan Lei, Xiao Li, Chun-Yin Lo, Jingxuan Li, Liwen Jiang, Xiaoqiang Yao

Full text read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Just a little prick: careful cell contacts enabled by ceramic nanostraws.Pflugers Archiv : European journal of physiology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. TRP Ion Channels in Immune Cells and Their Implications for Inflammation.International journal of molecular sciences · 2024
    Review
  13. Role of TRP Channels in Metabolism-Related Diseases.International journal of molecular sciences · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunting ZhangSchool of Biomedical Sciences, Heart and Vascular Institute, Li Ka Shing Institute of Health Science, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Fan YingSchool of Biomedical Sciences, Heart and Vascular Institute, Li Ka Shing Institute of Health Science, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Xiaoyu TianSchool of Biomedical Sciences, Heart and Vascular Institute, Li Ka Shing Institute of Health Science, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0003-3472-9898
Zhenchuan LeiSchool of Biomedical Sciences, Heart and Vascular Institute, Li Ka Shing Institute of Health Science, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Xiao LiSchool of Biomedical Sciences, Heart and Vascular Institute, Li Ka Shing Institute of Health Science, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Chun-Yin LoSchool of Biomedical Sciences, Heart and Vascular Institute, Li Ka Shing Institute of Health Science, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0001-7554-6014
Jingxuan LiSchool of Biomedical Sciences, Heart and Vascular Institute, Li Ka Shing Institute of Health Science, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Liwen JiangCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-7829-1472
Xiaoqiang YaoSchool of Biomedical Sciences, Heart and Vascular Institute, Li Ka Shing Institute of Health Science, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-0687-8186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a chronic inflammatory arterial disease characterized by build-up of atheromatous plaque, which narrows the lumen of arteries. Hypercholesterolemia and excessive oxidative stress in arterial walls are among the main causative factors of atherosclerosis. Transient receptor potential channel M2 (TRPM2) is a Ca

Indexed as

AtherosclerosisHypercholesterolemiaPlaque, AtheroscleroticTransient Receptor Potential ChannelsTRPM Cation ChannelsAnimalsDisease Models, AnimalEndothelial CellsInflammationMiceProprotein Convertase 9Reactive Oxygen SpeciesPCSK9 protein, humanProprotein Convertase 9Reactive Oxygen SpeciesTransient Receptor Potential ChannelsTRPM2 protein, mouseTRPM Cation ChannelsatherosclerosisROSTRPM2

Identifiers

PMID35563730
PMCPMC9103947

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.