Evidence map›Paper›PMID 35563546›Full record

ArticleInternational journal of molecular sciences2022

RNase 7 Inhibits Uropathogenic

Chen-Hsun Ho, Pin-Wen Liao, Chia-Kwung Fan, Shih-Ping Liu, Po-Ching Cheng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Immune defenses in the urinary tract.Trends in immunology · 2023
    Review
  7. Antimicrobial Peptide LCN2 Inhibited UropathogenicInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Chen-Hsun HoDivision of Urology, Department of Surgery, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan.
Pin-Wen LiaoSchool of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Chia-Kwung FanDepartment of Molecular Parasitology and Tropical Diseases, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-5579-8169
Shih-Ping LiuDepartment of Urology, National Taiwan University Hospital and College of Medicine, Taipei 10002, Taiwan.
Po-Ching ChengDepartment of Molecular Parasitology and Tropical Diseases, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-1172-2485
Fu Jen Catholic University · TWTaipei Medical University · TWNational Taiwan University Hospital · TW

Funding

grant from Shin Kong Memorial Wu Ho-Su Hospital, Taipei, Taiwan. 2022SKHBDR001
6 · The paper itself

Abstract

Antimicrobial peptides (AMPs), which are natural antibiotics, protect against pathogens invading the urinary tract. RNase 7 with antimicrobial properties has rapid and powerful suppressive effects against Gram-positive and Gram-negative bacterial infections. However, its detailed antibacterial mechanisms have not been fully determined. Here, we investigate whether RNase 7 had an impact on bladder cells under uropathogenic

Indexed as

Escherichia coli InfectionsRibonucleasesUrinary Tract InfectionsUropathogenic Escherichia coliEpithelial CellsFemaleGlucoseHumansInflammationInterleukin-6Interleukin-8MaleSignal TransductionToll-Like Receptor 4Urinary BladderGlucoseInterleukin-6Interleukin-8Ribonuclease 7RibonucleasesToll-Like Receptor 4antimicrobial peptideinflammatory responsesJAK/STAT signaling pathwayRNase 7urinary tract infectionuropathogenic Escherichia coli

Identifiers

PMID35563546
PMCPMC9102358
OpenAlexW4229052988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.