Evidence map›Paper›PMID 35563493›Full record

ArticleInternational journal of molecular sciences2022

Suppression of the Proliferation of Huh7 Hepatoma Cells Involving the Downregulation of Mutant p53 Protein and Inactivation of the STAT 3 Pathway with Ailanthoidol.

Tsui-Hwa Tseng, Chau-Jong Wang, Yean-Jang Lee, Yi-Chia Shao, Chien-Heng Shen, Ko-Chao Lee, Shui-Yi Tung, Hsing-Chun Kuo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Tsui-Hwa TsengDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung 40201, Taiwan.
Chau-Jong WangDepartment of Health Diet and Industry Management, Chung Shan Medical University, Taichung 40201, Taiwan.
Yean-Jang LeeDepartment of Chemistry, National Changhua University of Education, Changhua 50007, Taiwan.
Yi-Chia ShaoDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung 40201, Taiwan.
Chien-Heng ShenDepartment of Hepato-Gastroenterology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Ko-Chao LeeDivision of Colorectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Shui-Yi TungDepartment of Hepato-Gastroenterology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Hsing-Chun KuoDivision of Basic Medical Sciences, Department of Nursing, Chang Gung University of Science and Technology, Chiayi 61363, Taiwan.ORCID 0000-0002-8993-1615
Chang Gung University · TWChung Shan Medical University Hospital · TWChang Gung University of Science and Technology · TWChiayi Chang Gung Memorial Hospital · TWChung Shan Medical University · TWNational Changhua University of Education · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ailanthoidol (ATD) has been isolated from the barks of

Indexed as

BenzofuransCarcinoma, HepatocellularLiver NeoplasmsAminosalicylic AcidsApoptosisBenzenesulfonatesCell Line, TumorCell ProliferationCyclin D1Down-RegulationHumansMutant ProteinsProto-Oncogene Proteins c-bcl-2Signal TransductionSTAT3 Transcription FactorTumor Suppressor Protein p53ailanthoidolAminosalicylic AcidsBenzenesulfonatesBenzofuransCyclin D1Mutant ProteinsNSC 74859Proto-Oncogene Proteins c-bcl-2STAT3 Transcription FactorTumor Suppressor Protein p53ailanthoidolapoptosiscell cyclehepatomamutant p53STAT3

Identifiers

PMID35563493
PMCPMC9099615
OpenAlexW4229051551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.