Evidence map›Paper›PMID 35563489›Full record

ArticleInternational journal of molecular sciences2022

Topological and Multivalent Effects in Glycofullerene Oligomers as EBOLA Virus Inhibitors.

Javier Ramos-Soriano, Beatriz M Illescas, Alfonso Pérez-Sánchez, Raquel Sánchez-Bento, Fátima Lasala, Javier Rojo, Rafael Delgado, Nazario Martín

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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  4. Highly aqueously stable CSmart medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Javier Ramos-SorianoDepartamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain.ORCID 0000-0002-3054-0679
Beatriz M IllescasDepartamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain.ORCID 0000-0002-4727-8291
Alfonso Pérez-SánchezDepartamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain.
Raquel Sánchez-BentoDepartamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain.
Fátima LasalaLaboratorio de Microbiología Molecular, Instituto de Investigación Hospital 12 de Octubre (imas12), 28041 Madrid, Spain.
Javier RojoGlycosystems Laboratory, Instituto de Investigaciones Químicas (IIQ), CSIC-Universidad de Sevilla, Av. Américo Vespucio 49, 41092 Seville, Spain.
Rafael DelgadoLaboratorio de Microbiología Molecular, Instituto de Investigación Hospital 12 de Octubre (imas12), 28041 Madrid, Spain.ORCID 0000-0002-6912-4736
Nazario MartínDepartamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040 Madrid, Spain.
Universidad Complutense de Madrid · ESResearch Institute Hospital 12 de Octubre · ESInstituto de Investigaciones Químicas · ES

Funding

European Commission Horizon 2020 Framework Programme 731868 project VIRUSCAN FETPROACT-2016, and 101046084 project EPIC-CROWN-2Fundación Caixa-Health Research HR18-00469 project StopEbolaInstituto de Investigación Carlos III FIS PI1801007 and PI2100989Ministerio de Ciencia e Innovación PID2020-115120GB-I00, PID2020-114653RB-I00 and PID2020-118403GB-I00
6 · The paper itself

Abstract

The synthesis of new biocompatible antiviral materials to fight against the development of multidrug resistance is being widely explored. Due to their unique globular structure and excellent properties, [60]fullerene-based antivirals are very promising bioconjugates. In this work, fullerene derivatives with different topologies and number of glycofullerene units were synthesized by using a SPAAC copper free strategy. This procedure allowed the synthesis of compounds

Indexed as

EbolavirusFullerenesHemorrhagic Fever, EbolaAntiviral AgentsHumansMannoseAntiviral AgentsFullerenesMannoseantiviralsclick chemistryDC-SIGNEbola virusglycofullerene

Identifiers

PMID35563489
PMCPMC9131134
OpenAlexW4225421446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.