ReviewInternational journal of molecular sciences2022
A Review of Toxicity Mechanism Studies of Electronic Cigarettes on Respiratory System.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Association between current e-cigarette use and chronic obstructive pulmonary disease: a meta-analysis focusing on exclusive e-cigarette users.Frontiers in public health · 2026Pooled it
- Association of electronic cigarette use and risk of COPD: a systematic review and meta-analysis.NPJ primary care respiratory medicine · 2025Pooled it
- Nicotine analogs in e-cigarettes: unrecognized health risks and insufficient regulatory oversight.Toxicological sciences : an official journal of the Society of Toxicology · 2026Article
- Proximity and density of tobacco retail locations to Kentucky schools and the relationship to youth perceptions of harm and susceptibility to e-cigarette use.BMC public health · 2026Article
- Exposure to electronic cigarette aerosols triggers alterations in genomic DNA methylation that impacts cancer pathways in mice.Inhalation toxicology · 2026Article
- Vape flavoring chemicals and oral fibroblast viability.Anatomy & cell biology · 2026Review
- Spirometric Lung Function Among Smokers and Non-Smokers: A Cross-Sectional Study in University Students.International journal of environmental research and public health · 2026Article
- Prevalence of adverse respiratory symptoms among e-cigarette users at Imam Mohammad Ibn Saud Islamic University in Riyadh, Saudi Arabia: A cross-sectional study.Journal of family medicine and primary care · 2026Article
- Strengthening Tobacco Product Regulation: Addressing Challenges and Strategies for Articles 9 and 10 Implementation.Health care analysis : HCA : journal of health philosophy and policy · 2025Article
- Attitudes of people diagnosed with cancer and cancer care providers towards use of nicotine vaping products in high-income countries: a scoping review.Journal of cancer survivorship : research and practice · 2025Article
- Toxicity of humectants propylene glycol and vegetable glycerin in electronic nicotine delivery systems.Toxicology letters · 2025Review
- Therapeutic effects of single-clove garlic extract on nicotine-induced inflammation and histopathological changes in rats.Open veterinary journal · 2025Review
- Elemental composition of vaping and smoking aerosols: Influence of liquid type and tank conditions.PloS one · 2025Article
- Impact of smoking exposure on meibomian gland morphology and tear film stability: a cross-sectional study.Frontiers in medicine · 2025Article
- E-cigarettes and arterial health: A review of the link between vaping and atherosclerosis progression.World journal of cardiology · 2024Review
- A Review of the Toxicity of Ingredients in e-Cigarettes, Including Those Ingredients Having the FDA's "Generally Recognized as Safe (GRAS)" Regulatory Status for Use in Food.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Review
- Assessing vitamin E acetate as a proxy for E-cigarette additives in a realistic pulmonary surfactant model.Scientific reports · 2024Article
- Review
- On the extension of the use of a standard operating procedure for nicotine, glycerol and propylene glycol analysis in e-liquids using mass spectrometry.Tobacco induced diseases · 2024Article
- Effects of e-cigarette smoking on periodontal health: A scoping review.PLOS global public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electronic cigarettes (e-cigarettes) have attracted much attention as a new substitute for conventional cigarettes. E-cigarettes are first exposed to the respiratory system after inhalation, and studies on the toxicity mechanisms of e-cigarettes have been reported. Current research shows that e-cigarette exposure may have potentially harmful effects on cells, animals, and humans, while the safety evaluation of the long-term effects of e-cigarette use is still unknown. Similar but not identical to conventional cigarettes, the toxicity mechanisms of e-cigarettes are mainly manifested in oxidative stress, inflammatory responses, and DNA damage. This review will summarize the toxicity mechanisms and signal pathways of conventional cigarettes and e-cigarettes concerning the respiratory system, which could give researchers a better understanding and direction on the effects of e-cigarettes on our health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.