Evidence map›Paper›PMID 35563399›Full record

ArticleInternational journal of molecular sciences2022

Metalloendopeptidase ADAM-like Decysin 1 (ADAMDEC1) in Colonic Subepithelial PDGFRα

Se Eun Ha, Brian G Jorgensen, Lai Wei, Byungchang Jin, Min-Seob Kim, Sandra M Poudrier, Rajan Singh, Allison Bartlett, Hannah Zogg, Sei Kim and 12 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. CaPhysiological reviews · 2024
    Review
  5. Article
  6. ADAMDEC1 accelerates GBM progressionFrontiers in oncology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 2 countries.

Se Eun HaDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.ORCID 0000-0001-6063-5559
Brian G JorgensenDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Lai WeiDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Byungchang JinDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Min-Seob KimDepartment of Physiology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan 54538, Korea.
Sandra M PoudrierDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Rajan SinghDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.ORCID 0000-0001-5500-1949
Allison BartlettDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.ORCID 0000-0002-6442-4684
Hannah ZoggDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.ORCID 0000-0002-2413-157X
Sei KimDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Gain BaekDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Masaaki KurahashiDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, University of Iowa, Iowa City, IA 52242, USA.
Moon-Young LeeDepartment of Physiology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan 54538, Korea.ORCID 0000-0003-4956-9241
Yong-Sung KimDepartment of Physiology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan 54538, Korea.ORCID 0000-0001-8836-4818
Suck-Chei ChoiDepartment of gastroenterology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan 54538, Korea.
Kent C SasseSasse Surgical Associates, Reno, NV 89502, USA.
Samuel J S RubinGastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-7335-3868
Andres Gottfried-BlackmoreGastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-3563-3727
Laren BeckerGastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Aida HabtezionGastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Kenton M SandersDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.
Seungil RoDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA.ORCID 0000-0003-0861-8334
University of Nevada, Reno · USStanford University · USWonkwang University · KRUniversity of Iowa · US

Funding

Tissue, Cell and Tissue Culture CoreP01DK041315 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KEEF, KATHLEEN D · 1989 to 2018
$26.3M
Inhibitory mechanisms of PDGFRa+ interstitial cells in gastrointestinal motilityR01DK091336 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KURAHASHI, MASAAKI · 2013 to 2022
$4.3M
Roles of DNA methylation in gastrointestinal smooth muscle cellsR01DK094886 · NIDDK · UNIVERSITY OF NEVADA RENO · PI RO, SEUNGIL · 2012 to 2016
$1.5M
Engineering of functional smooth muscle cells from gastrointestinal myofibroblastR01DK103055 · NIDDK · UNIVERSITY OF NEVADA RENO · PI RO, SEUNGIL · 2015 to 2018
$1.3M
NIDDK NIH HHS P01 DK041315NIDDK NIH HHS R01 DK091336NIDDK NIH HHS R01 DK094886NIDDK NIH HHS R01 DK103055NIH HHS P01-DK41315NIH HHS R01DK094886NIH HHS R01DK103055
6 · The paper itself

Abstract

Metalloendopeptidase ADAM-Like Decysin 1 (ADAMDEC1) is an anti-inflammatory peptidase that is almost exclusively expressed in the gastrointestinal (GI) tract. We have recently found abundant and selective expression of Adamdec1 in colonic mucosal PDGFRα

Indexed as

ADAM ProteinsColitisCrohn DiseaseInflammatory Bowel DiseasesAnimalsBiomarkersColonIntestinal MucosaMiceReceptor, Platelet-Derived Growth Factor alphaRNA, MessengerADAM ProteinsBiomarkersdecysinReceptor, Platelet-Derived Growth Factor alphaRNA, MessengerADAMDEC1Crohn’s diseaseDSS colitisinflammatory bowel diseasemucosal PDGFRα+ cells

Identifiers

PMID35563399
PMCPMC9103908
OpenAlexW4225248481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.