Evidence map›Paper›PMID 35563381›Full record

ReviewInternational journal of molecular sciences2022

Preservation of Organs to Be Transplanted: An Essential Step in the Transplant Process.

Maryne Lepoittevin, Sébastien Giraud, Thomas Kerforne, Benoit Barrou, Lionel Badet, Petru Bucur, Ephrem Salamé, Claire Goumard, Eric Savier, Julien Branchereau and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  6. Molecular Frontiers in Transplantation-Induced Ischemia-Reperfusion Injury.International journal of molecular sciences · 2023
    Article
  7. Effects of T3 Administration onTransplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Maryne LepoittevinBiochemistry Department, CHU Poitiers, 86021 Poitiers, France.
Sébastien GiraudBiochemistry Department, CHU Poitiers, 86021 Poitiers, France.
Thomas KerforneFaculty of Medicine and Pharmacy, University of Poitiers, 86073 Poitiers, France.
Benoit BarrouINSERM U1313, IRMETIST, 86021 Poitiers, France.
Lionel BadetINSERM U1313, IRMETIST, 86021 Poitiers, France.
Petru BucurSociété Francophone de Transplantation et de l'Ecole Francophone pour le Prélèvement Multi-Organes, 75013 Paris, France.
Ephrem SalaméSociété Francophone de Transplantation et de l'Ecole Francophone pour le Prélèvement Multi-Organes, 75013 Paris, France.
Claire GoumardSociété Francophone de Transplantation et de l'Ecole Francophone pour le Prélèvement Multi-Organes, 75013 Paris, France.
Eric SavierSociété Francophone de Transplantation et de l'Ecole Francophone pour le Prélèvement Multi-Organes, 75013 Paris, France.ORCID 0000-0003-4131-2222
Julien BranchereauSociété Francophone de Transplantation et de l'Ecole Francophone pour le Prélèvement Multi-Organes, 75013 Paris, France.ORCID 0000-0002-8460-9352
Pascal BattistellaSociété Francophone de Transplantation et de l'Ecole Francophone pour le Prélèvement Multi-Organes, 75013 Paris, France.
Olaf MercierSociété Francophone de Transplantation et de l'Ecole Francophone pour le Prélèvement Multi-Organes, 75013 Paris, France.
Sacha MussotSociété Francophone de Transplantation et de l'Ecole Francophone pour le Prélèvement Multi-Organes, 75013 Paris, France.
Thierry HauetBiochemistry Department, CHU Poitiers, 86021 Poitiers, France.ORCID 0000-0002-0117-071X
Raphael ThuillierBiochemistry Department, CHU Poitiers, 86021 Poitiers, France.ORCID 0000-0002-7482-0031
Inserm · FRCentre Hospitalier Universitaire de Tours · FRSorbonne Université · FRCentre Chirurgical Marie Lannelongue · FRUniversité Claude Bernard Lyon 1 · FRUniversité de Montpellier · FRUniversité Paris-Saclay · FR

Funding

Centre Hospitalier Universitaire de PoitiersInsermUniversity of Poitiers
6 · The paper itself

Abstract

Organ transplantation remains the treatment of last resort in case of failure of a vital organ (lung, liver, heart, intestine) or non-vital organ (essentially the kidney and pancreas) for which supplementary treatments exist. It remains the best alternative both in terms of quality-of-life and life expectancy for patients and of public health expenditure. Unfortunately, organ shortage remains a widespread issue, as on average only about 25% of patients waiting for an organ are transplanted each year. This situation has led to the consideration of recent donor populations (deceased by brain death with extended criteria or deceased after circulatory arrest). These organs are sensitive to the conditions of conservation during the ischemia phase, which have an impact on the graft's short- and long-term fate. This evolution necessitates a more adapted management of organ donation and the optimization of preservation conditions. In this general review, the different aspects of preservation will be considered. Initially done by hypothermia with the help of specific solutions, preservation is evolving with oxygenated perfusion, in hypothermia or normothermia, aiming at maintaining tissue metabolism. Preservation time is also becoming a unique evaluation window to predict organ quality, allowing repair and/or optimization of recipient choice.

Indexed as

HypothermiaTissue and Organ ProcurementHumansOrgan PreservationPerfusionTissue Donorskidney transplantationorgan preservationoxygentemperature

Identifiers

PMID35563381
PMCPMC9104613
OpenAlexW4225165258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.