Evidence map›Paper›PMID 35563239›Full record

ArticleInternational journal of molecular sciences2022

Identification of

Samia Nisar, Magali Torres, Alassane Thiam, Bruno Pouvelle, Florian Rosier, Frederic Gallardo, Oumar Ka, Babacar Mbengue, Rokhaya Ndiaye Diallo, Laura Brosseau and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Human genetic variations conferring resistance to malaria.Journal of translational medicine · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. A robust fluorescence-based assay for human erythrocyte CaEuropean biophysics journal : EBJ · 2023
    Article
  16. Article
  17. Impact ofFrontiers in genetics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Samia NisarMarMara Institute, Aix-Marseille University INSERM, TAGC, UMR_S_1090, 13288 Marseille, France.
Magali TorresMarMara Institute, Aix-Marseille University INSERM, TAGC, UMR_S_1090, 13288 Marseille, France.
Alassane ThiamUnité d'Immunogénétique, Institut Pasteur de Dakar, Dakar BP220, Senegal.
Bruno PouvelleMarMara Institute, Aix-Marseille University INSERM, TAGC, UMR_S_1090, 13288 Marseille, France.
Florian RosierMarMara Institute, Aix-Marseille University INSERM, TAGC, UMR_S_1090, 13288 Marseille, France.ORCID 0000-0002-4363-8093
Frederic GallardoMarMara Institute, Aix-Marseille University INSERM, TAGC, UMR_S_1090, 13288 Marseille, France.
Oumar KaService d'Immunologie, Université Cheikh Anta Diop de Dakar, Dakar BP5005, Senegal.
Babacar MbengueService d'Immunologie, Université Cheikh Anta Diop de Dakar, Dakar BP5005, Senegal.
Rokhaya Ndiaye DialloService de Génétique Humaine, Faculté de Médecine, de Pharmacie et d'Odontologie, UCAD, Dakar BP5005, Senegal.
Laura BrosseauMarMara Institute, Aix-Marseille University INSERM, TAGC, UMR_S_1090, 13288 Marseille, France.ORCID 0000-0002-4911-2287
Salvatore SpicugliaMarMara Institute, Aix-Marseille University INSERM, TAGC, UMR_S_1090, 13288 Marseille, France.
Alioune DieyeUnité d'Immunogénétique, Institut Pasteur de Dakar, Dakar BP220, Senegal.
Sandrine MarquetMarMara Institute, Aix-Marseille University INSERM, TAGC, UMR_S_1090, 13288 Marseille, France.ORCID 0000-0001-7011-6496
Pascal RihetMarMara Institute, Aix-Marseille University INSERM, TAGC, UMR_S_1090, 13288 Marseille, France.ORCID 0000-0002-9459-3905

Funding

Aix-Marseille University Funding for researchCheikh Anta Diop University African Higher Education Centers of Excellence projectFrench ministry of research Florian Rosier's PhD fellowshipHigher Education Commission Samia Nisar's PhD fellowshipInserm Funding for researchInstitut Pasteur Grant to finance Alassane Thiam's stay at TAGC in Marseille
6 · The paper itself

Abstract

Genome-wide association studies for severe malaria (SM) have identified 30 genetic variants mostly located in non-coding regions. Here, we aimed to identify potential causal genetic variants located in these loci and demonstrate their functional activity. We systematically investigated the regulatory effect of the SNPs in linkage disequilibrium (LD) with the malaria-associated genetic variants. Annotating and prioritizing genetic variants led to the identification of a regulatory region containing five

Indexed as

Genome-Wide Association StudyMalariaGenetic Predisposition to DiseaseHumansPlasma Membrane Calcium-Transporting ATPasesPolymorphism, Single NucleotideRegulatory Sequences, Nucleic AcidATP2B4 protein, humanPlasma Membrane Calcium-Transporting ATPasesATP2B4calciumCRISPR-cas9enhancerfunctional genomicsgene reportermalariapromoterregulatory elementSNP

Identifiers

PMID35563239
PMCPMC9101746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.