Evidence map›Paper›PMID 35563162›Full record

ArticleInternational journal of molecular sciences2022

Quantification and Improvement of the Dynamics of Human Serum Albumin and Glycated Human Serum Albumin with Astaxanthin/Astaxanthin-Metal Ion Complexes: Physico-Chemical and Computational Approaches.

Syahputra Wibowo, Jessica Costa, Maria Camilla Baratto, Rebecca Pogni, Sri Widyarti, Akhmad Sabarudin, Koichi Matsuo, Sutiman Bambang Sumitro

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Novel mutation sites in theJournal of advanced veterinary and animal research · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Syahputra WibowoDepartment of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Jl. Veteran, Malang 65145, East Java, Indonesia.ORCID 0000-0003-3979-4277
Jessica CostaDepartment of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.
Maria Camilla BarattoDepartment of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.ORCID 0000-0003-2258-779X
Rebecca PogniDepartment of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.ORCID 0000-0001-6681-1592
Sri WidyartiDepartment of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Jl. Veteran, Malang 65145, East Java, Indonesia.ORCID 0000-0002-9100-7544
Akhmad SabarudinDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Brawijaya University, Jl. Veteran, Malang 65145, East Java, Indonesia.ORCID 0000-0002-3096-5087
Koichi MatsuoHiroshima Synchrotron Radiation Center, Hiroshima University, Higashi-Hiroshima 739-0046, Japan.ORCID 0000-0001-8166-544X
Sutiman Bambang SumitroDepartment of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Jl. Veteran, Malang 65145, East Java, Indonesia.ORCID 0000-0001-8001-4338
University of Brawijaya · IDUniversity of Siena · ITHiroshima University · JP

Funding

PKPI-PMDSU PKPI-PMDSUPMDSU PMDSUWCU-UB WCU-UB
6 · The paper itself

Abstract

Glycated human serum albumin (gHSA) undergoes conformational changes and unfolding events caused by free radicals. The glycation process results in a reduced ability of albumin to act as an endogenous scavenger and transporter protein in diabetes mellitus type 2 (T2DM) patients. Astaxanthin (ASX) in native form and complexed with metal ions (Cu

Indexed as

Coordination ComplexesSerum Albumin, HumanCircular DichroismHumansIonsMolecular Docking SimulationProtein BindingSerum AlbuminXanthophyllsastaxanthineCoordination ComplexesIonsSerum AlbuminSerum Albumin, HumanXanthophyllsantioxidantsastaxanthinastaxanthin metal complexesdiabetes mellitus type 2glycated human serum albuminhuman serum albuminmulti-techniques and computational analysis

Identifiers

PMID35563162
PMCPMC9104927
OpenAlexW4224941696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.