Evidence map›Paper›PMID 35563128›Full record

ReviewInternational journal of molecular sciences2022

Research on Graphene and Its Derivatives in Oral Disease Treatment.

Chengcheng Liu, Dan Tan, Xiaoli Chen, Jinfeng Liao, Leng Wu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Overexpression of ASFrontiers in cellular and infection microbiology · 2026
    Article
  4. Review
  5. Graphene in dentistry: transformative applications and innovations.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  6. Article
  7. Review
  8. The regulatory effect of TiOBMC oral health · 2024
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Chengcheng LiuState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Periodontics, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Dan TanDepartment of Periodontics and Oral Mucosal Diseases, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou 646000, China.
Xiaoli ChenState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Periodontics, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Jinfeng LiaoState Key Laboratory of Oral Diseases, West China School & Hospital of Stomatology, Sichuan University, Chengdu 610041, China.ORCID 0000-0003-4498-5270
Leng WuDepartment of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Sichuan University · CNSouthwest Medical University · CNWuhan University · CN

Funding

the Fundamental Research Funds for Central Universities No numberthe National Natural Science Foundation 32171354Youth Innovation Promotion Association of Chinese Academy of Sciences No number
6 · The paper itself

Abstract

Oral diseases present a global public health problem that imposes heavy financial burdens on individuals and health-care systems. Most oral health conditions can be treated in their early stage. Even if the early symptoms of oral diseases do not seem to cause significant discomfort, prompt treatment is essential for preventing their progression. Biomaterials with superior properties enable dental therapies with applications in restoration, therapeutic drug/protein delivery, and tissue regeneration. Graphene nanomaterials have many unique mechanical and physiochemical properties and can respond to the complex oral microenvironment, which includes oral microbiota colonization and high masticatory force. Research on graphene nanomaterials in dentistry, especially in caries, periodontitis therapy, and implant coatings, is progressing rapidly. Here, we review the development of graphene and its derivatives for dental disease therapy.

Indexed as

GraphiteNanostructuresBiocompatible MaterialsDrug Delivery SystemsHumansTissue EngineeringBiocompatible MaterialsGraphitecariesgraphenegraphene oxideosseointegrationperiodontitispulp infection

Identifiers

PMID35563128
PMCPMC9104291
OpenAlexW4224466339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.