Evidence map›Paper›PMID 35563100›Full record

ReviewInternational journal of molecular sciences2022

Beyond BRCA: The Emerging Significance of DNA Damage Response and Personalized Treatment in Pancreatic and Prostate Cancer Patients.

Bruna Dalmasso, Alberto Puccini, Fabio Catalano, Roberto Borea, Maria Laura Iaia, William Bruno, Giuseppe Fornarini, Stefania Sciallero, Sara Elena Rebuzzi, Paola Ghiorzo

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  3. Cancer-associated TRF1 mutations alter PARP1 interaction dynamics: an in silico study.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Bruna DalmassoIRCCS Ospedale Policlinico San Martino, Genetics of Rare Cancers, 16132 Genoa, Italy.ORCID 0000-0002-1534-0521
Alberto PucciniIRCCS Ospedale Policlinico San Martino, Medical Oncology Unit 1, 16132 Genoa, Italy.ORCID 0000-0002-2492-4043
Fabio CatalanoIRCCS Ospedale Policlinico San Martino, Medical Oncology Unit 1, 16132 Genoa, Italy.
Roberto BoreaIRCCS Ospedale Policlinico San Martino, Medical Oncology Unit 1, 16132 Genoa, Italy.ORCID 0000-0001-5403-0916
Maria Laura IaiaIRCCS Ospedale Policlinico San Martino, Medical Oncology Unit 1, 16132 Genoa, Italy.
William BrunoIRCCS Ospedale Policlinico San Martino, Genetics of Rare Cancers, 16132 Genoa, Italy.ORCID 0000-0002-0337-0168
Giuseppe FornariniIRCCS Ospedale Policlinico San Martino, Medical Oncology Unit 1, 16132 Genoa, Italy.ORCID 0000-0003-4754-6572
Stefania ScialleroIRCCS Ospedale Policlinico San Martino, Medical Oncology Unit 1, 16132 Genoa, Italy.
Sara Elena RebuzziDepartment of Internal Medicine and Medical Specialties, University of Genoa, 16132 Genoa, Italy.ORCID 0000-0003-0546-6304
Paola GhiorzoIRCCS Ospedale Policlinico San Martino, Genetics of Rare Cancers, 16132 Genoa, Italy.ORCID 0000-0002-3651-8173
Ospedale Policlinico San Martino · ITOspedale San Paolo · IT

Funding

Associazione Ricerca Tumori Rari ed Ereditari (AR3) onlus NALega Italiana per la Lotta ai Tumori 5x1000 IG 2019 (P.G)Ministero della Salute Ospedale Policlinico San Martino Ricerca Corrente and 5x1000 (P.G.)Ministero della Salute Ricerca Corrente 2018-2021 grants (S.E.R. and G.F.)
6 · The paper itself

Abstract

The

Indexed as

Precision MedicineProstatic NeoplasmsDNA DamageHumansMalePancreatic NeoplasmsBRCADNA damage responsegeneticshomologous recombinationmismatch repairpancreatic cancerPARP inhibitorsprostate cancer

Identifiers

PMID35563100
PMCPMC9099822
OpenAlexW4224310598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.