Evidence map›Paper›PMID 35563098›Full record

ArticleInternational journal of molecular sciences2022

Notch-Sox9 Axis Mediates Hepatocyte Dedifferentiation in

Junhui Sun, Qi Chen, Jianlong Ma

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Junhui SunInstitute of Developmental Biology and Regenerative Medicine, Southwest University, Beibei, Chongqing 400715, China.
Qi ChenInstitute of Developmental Biology and Regenerative Medicine, Southwest University, Beibei, Chongqing 400715, China.
Jianlong MaInstitute of Developmental Biology and Regenerative Medicine, Southwest University, Beibei, Chongqing 400715, China.
Southwest University · CN

Funding

Postdoctoral Program for Innovative Talent Support of Chongqing CQBX201906
6 · The paper itself

Abstract

Liver cancer is one of the most prevalent cancers in humans. Hepatocytes normally undergo dedifferentiation after the onset of hepatocellular carcinoma, which in turn facilitates the progression of cancer. Although the process of hepatocellular carcinoma dedifferentiation is of significant research and clinical value, the cellular and molecular mechanisms underlying it are still not fully characterized. We constructed a zebrafish liver cancer model based on overexpression of the oncogene

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAnimalsCarcinogenesisHepatocytesProto-Oncogene Proteins p21(ras)ZebrafishZebrafish ProteinsKras protein, zebrafishProto-Oncogene Proteins p21(ras)Zebrafish Proteinscancer modeldedifferentiationhepatocellular carcinomaNotchSox9

Identifiers

PMID35563098
PMCPMC9103821
OpenAlexW4224311557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.