Evidence map›Paper›PMID 35562949›Full record

ReviewInternational journal of molecular sciences2022

Metabolic Activation and DNA Interactions of Carcinogenic

Yupeng Li, Stephen S Hecht

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 164 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Complex versus simpleScience advances · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Low-levelEnvironmental science : water research & technology · 2025
    Article
  15. Interplay between the gut microbiota, its metabolites and carcinogens.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. In vivo and in vitro genotoxicity of N-nitrosopyrrolidine following UVA irradiation.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2025
    Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Yupeng LiMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0001-5403-5880
Stephen S HechtMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
University of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Jeffrey S. Miller · 1998 to 2026
$100.4M
METABOLISM OF CARCINOGENIC TOBACCO SPECIFIC NITROSAMINESR01CA081301 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI STEPHEN S HECHT · 1999 to 2026
$7.1M
Metabolism of Carcinogenic Tobacco-Specific NitrosaminesR37CA081301 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI HECHT, STEPHEN S · 2004 to 2013
$5.5M
NCI NIH HHS CA-77598NCI NIH HHS CA-81301NCI NIH HHS R01 CA081301
6 · The paper itself

Abstract

Carcinogenic

Indexed as

NitrosaminesActivation, MetabolicAnimalsCarcinogensCytochrome P-450 Enzyme SystemDNADNA AdductsHumansCarcinogensCytochrome P-450 Enzyme SystemDNADNA AdductsNitrosaminesDNA adductsmetabolismNDMAN-nitrosaminesP450s

Identifiers

PMID35562949
PMCPMC9105260
OpenAlexW4224260803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.