Evidence map›Paper›PMID 35562943›Full record

ReviewInternational journal of molecular sciences2022

Circular RNAs in Pregnancy and the Placenta.

Anya L Arthurs, Tanja Jankovic-Karasoulos, Melanie D Smith, Claire T Roberts

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. DNA methylation of theiScience · 2026
    Article
  2. Placental Alterations in Autism Spectrum Disorder: An In Silico Approach to circRNA-miRNA-mRNA Networks.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Role of circular RNAs in lung cancer.Frontiers in genetics · 2024
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anya L ArthursFlinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.ORCID 0000-0002-4382-0610
Tanja Jankovic-KarasoulosFlinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Melanie D SmithFlinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.ORCID 0000-0001-7016-8245
Claire T RobertsFlinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.ORCID 0000-0002-9250-2192
Flinders University · AU

Funding

National Health and Medical Research Council GNT1174971
6 · The paper itself

Abstract

The emerging field of circular RNAs (circRNAs) has identified their novel roles in the development and function of many cancers and inspired the interest of many researchers. circRNAs are also found throughout the healthy body, as well as in other pathological states, but while research into the function and abundance of circRNAs has progressed, our overall understanding of these molecules remains primitive. Importantly, recent studies are elucidating new roles for circRNAs in pregnancy, particularly in the placenta. Given that many of the genes responsible for circRNA production in cancer are also highly expressed in the placenta, it is likely that the same genes act in the production of circRNAs in the placenta. Furthermore, placental development can be referred to as 'controlled cancer', as it shares many key signalling pathways and hallmarks with tumour growth and metastasis. Hence, the roles of circRNAs in this field are important to study with respect to pregnancy success but also may provide novel insights for cancer progression. This review illuminates the known roles of circRNAs in pregnancy and the placenta, as well as demonstrating differential placental expressions of circRNAs between complicated and uncomplicated pregnancies.

Indexed as

MicroRNAsRNA, CircularFemaleHumansPlacentaPregnancySignal TransductionMicroRNAsRNA, CircularcircRNAcircular RNAplacentapregnancyreproduction

Identifiers

PMID35562943
PMCPMC9100345
OpenAlexW4224267805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.