Evidence map›Paper›PMID 35562899›Full record

ArticleInternational journal of molecular sciences2022

Human α-Defensin-6 Neutralizes

Lara Barthold, Sebastian Heber, Christoph Q Schmidt, Marion Gradl, Gilbert Weidinger, Holger Barth, Stephan Fischer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Effects of Bile on PathogenicBiomolecules · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Trauma-toxicology: concepts, causes, complications.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lara BartholdInstitute of Pharmacology and Toxicology, Ulm University Medical Center, 89081 Ulm, Germany.
Sebastian HeberInstitute of Pharmacology and Toxicology, Ulm University Medical Center, 89081 Ulm, Germany.
Christoph Q SchmidtInstitute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University Medical Center, 89081 Ulm, Germany.
Marion GradlInstitute of Biochemistry and Molecular Biology, Ulm University, 89081 Ulm, Germany.
Gilbert WeidingerInstitute of Biochemistry and Molecular Biology, Ulm University, 89081 Ulm, Germany.
Holger BarthInstitute of Pharmacology and Toxicology, Ulm University Medical Center, 89081 Ulm, Germany.
Stephan FischerInstitute of Pharmacology and Toxicology, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0001-6862-2971
Universität Ulm · DE

Funding

Deutsche Forschungsgemeinschaft BA 2087/8-1, project no. 450938962 to H.BDeutsche Forschungsgemeinschaft Collaborative Research Center 1279 project no. 316249678, C02, funding to H.B.Deutsche Forschungsgemeinschaft Collaborative Research Center 1279 project no. 316249678, Z02, funding to G.W.Medical Faculty Ulm, University of Ulm Bausteinprogramm der Medizinischen Fakultät Modul 3.2 to S.F.
6 · The paper itself

Abstract

Rising incidences and mortalities have drawn attention to

Indexed as

alpha-DefensinsBacterial ToxinsClostridioides difficileClostridium InfectionsAnimalsAnti-Bacterial AgentsAntibodies, BacterialBacterial ProteinsEnterotoxinsHumansrho GTP-Binding ProteinsZebrafishalpha-DefensinsAnti-Bacterial AgentsAntibodies, BacterialBacterial ProteinsBacterial ToxinsDEFA6 protein, humanEnterotoxinsrho GTP-Binding Proteinsbacterial AB-type protein toxinsClostridioides difficile infectionshuman antimicrobial peptidelarge clostridial glucosylating toxins TcdA and TcdBtoxin inhibitorzebrafishα-defensin-6

Identifiers

PMID35562899
PMCPMC9101188
OpenAlexW4224245636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.