Evidence map›Paper›PMID 35562887›Full record

ArticleInternational journal of molecular sciences2022

Transcriptomic and Proteomic Analysis of CRISPR/Cas9-Mediated

Yu-Yuan Wang, Shih-Hsin Hsu, Hsin-Yao Tsai, Fu-Yu Cheng, Min-Chih Cheng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Neurological Diseases: A Molecular Genetic Perspective.International journal of molecular sciences · 2023
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yu-Yuan WangDepartment of Psychiatry, Yuli Branch, Taipei Veterans General Hospital, Hualien 98142, Taiwan.
Shih-Hsin HsuDepartment of Psychiatry, Yuli Branch, Taipei Veterans General Hospital, Hualien 98142, Taiwan.
Hsin-Yao TsaiDepartment of Psychiatry, Yuli Branch, Taipei Veterans General Hospital, Hualien 98142, Taiwan.
Fu-Yu ChengDepartment of Psychiatry, Yuli Branch, Taipei Veterans General Hospital, Hualien 98142, Taiwan.
Min-Chih ChengDepartment of Psychiatry, Yuli Branch, Taipei Veterans General Hospital, Hualien 98142, Taiwan.ORCID 0000-0002-2962-0911
Taipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arc/Arg3.1 (activity-regulated cytoskeletal-associated protein (ARC)) is a critical regulator of long-term synaptic plasticity and is involved in the pathophysiology of schizophrenia. The functions and mechanisms of human ARC action are poorly understood and worthy of further investigation. To investigate the function of the

Indexed as

ProteomicsTranscriptomeCarrier ProteinsChromatography, LiquidCRISPR-Cas SystemsHEK293 CellsHumansMicrofilament ProteinsMitochondrial ProteinsTandem Mass SpectrometryCarrier ProteinsFSCN1 protein, humanHint2 protein, humanMicrofilament ProteinsMitochondrial ProteinsARCCRISPR/Cas9HSPA1AproteomicsPSD95transcriptomics

Identifiers

PMID35562887
PMCPMC9101110
OpenAlexW4224247683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.