Evidence map›Paper›PMID 35562881›Full record

ArticleInternational journal of molecular sciences2022

Overexpression of Nucleolin and Associated Genes in Prostate Cancer.

Virginie Firlej, Pascale Soyeux, Maya Nourieh, Eric Huet, Fannie Semprez, Yves Allory, Arturo Londono-Vallejo, Alexandre de la Taille, Francis Vacherot, Damien Destouches

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Virginie FirlejUniv Paris Est Creteil, TRePCa, F-94010 Creteil, France.ORCID 0000-0003-4132-0695
Pascale SoyeuxUniv Paris Est Creteil, TRePCa, F-94010 Creteil, France.
Maya NouriehDepartment of Pathology, Institut Curie, F-92210 Saint-Cloud, France.
Eric HuetUniv Paris Est Creteil, TRePCa, F-94010 Creteil, France.ORCID 0000-0002-5541-5954
Fannie SemprezSPPIN-Saints-Pères Paris Institute for the Neurosciences, Université de Paris, CNRS, F-75006 Paris, France.
Yves AlloryDepartment of Pathology, Institut Curie, F-92210 Saint-Cloud, France.ORCID 0000-0002-5526-077X
Arturo Londono-VallejoInstitut Curie, PSL Research University, CNRS UMR 3244 « Telomeres and Cancer », F-75005 Paris, France.
Alexandre de la TailleUniv Paris Est Creteil, TRePCa, F-94010 Creteil, France.
Francis VacherotUniv Paris Est Creteil, TRePCa, F-94010 Creteil, France.
Damien DestouchesUniv Paris Est Creteil, TRePCa, F-94010 Creteil, France.ORCID 0000-0003-4959-2580
Université Paris-Est Créteil · FRCentre National de la Recherche Scientifique · FRInstitut Curie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is the second most frequent cancer and the fifth leading cause of cancer death in men worldwide. If local PCa presents a favorable prognosis, available treatments for advanced PCa display limiting benefits due to therapeutic resistances. Nucleolin (NCL) is a ubiquitous protein involved in numerous cell processes, such as ribosome biogenesis, cell cycles, or angiogenesis. NCL is overexpressed in several tumor types in which it has been proposed as a diagnostic and prognostic biomarker. In PCa, NCL has mainly been studied as a target for new therapeutic agents. Nevertheless, little data are available concerning its expression in patient tissues. Here, we investigated the expression of NCL using a new cohort from Mondor Hospital and data from published cohorts. Results were then compared with NCL expression using

Indexed as

Prostatic NeoplasmsRNA-Binding ProteinsBiomarkersHumansMaleNucleolinPhosphoproteinsBiomarkersNucleolinPhosphoproteinsRNA-Binding Proteinsbiomarkernucleolinprostate cancer

Identifiers

PMID35562881
PMCPMC9101690
OpenAlexW4224244829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.