ArticleBMC surgery2022
Influence of lower-limb mechanical axis on the curative effect of medial high tibial osteotomy for knee osteoarthritis.
Article in BMC surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Translating mechanobiology in osteoarthritis to biomaterial-informed therapeutic strategies.Mechanobiology in medicine · 2026Review
- Arthrokinematic and Magnetic Resonance Imaging-Based Outcomes of Customized Lateral Wedge Insoles in Medial Compartment Knee Osteoarthritis: Six-Month Interim Findings of a Prospective Cohort Study.Journal of orthopaedic case reports · 2026Article
- Changes in Balance Outcomes Following High Tibial Osteotomy in Patients With Knee Osteoarthritis: A Systematic Review.Health science reports · 2026Review
- High tibial osteotomy achieves unloading of the medial tibiofemoral compartment irrespective of arthritic status or medial collateral ligament release: A biomechanical assessment.Journal of experimental orthopaedics · 2026Article
- Medial closing wedge distal femoral osteotomy with patient-specific instrumentation: surgical technique, accuracy, and preliminary outcomes.Frontiers in surgery · 2026Article
- Distinct effects of three knee-preserving surgeries on hip-knee-ankle alignment in patients with knee osteoarthritis.Journal of orthopaedic surgery and research · 2025Article
- Comparison of the Miniaci and Dugdale techniques on functional outcomes in medial open wedge high tibial osteotomy.Journal of experimental orthopaedics · 2023Article
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Authors and funding
8 authors.
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Abstract
purposeTo investigate the effect of the ratio of the medial tibial plateau width to the total tibial plateau width on the therapeutic efficacy of high tibial osteotomy (HTO) on the medial side for the treatment of knee osteoarthritis.
methodsIn this study, we retrospectively analyzed information of 278 patients who underwent medial HTO for knee osteoarthritis with varus deformity. The Tinetti Gait and Balance Assessment Tool, the Visual Analog Scale (VAS), and the Knee Society Scoring System (KSS) were used to comprehensively evaluate the function of the knee joint after HTO.
resultsAfter adjusting for potential confounding factors (i.e., age, gender, body mass index/BMI, and surgical site), the Tinetti assessment score was optimized when the degree of correction was 53.67%, with the β-value on the left and right sides of the inflection point of 0.49 (confidence interval, CI: 0.20, 0.78, P = 0.0009) and- 0.26 (95% CI: - 0.30, - 0.22, P < 0.0001), respectively. The KSS score was optimized when the degree of correction was 55.45%, with the β-value on the left and right sides of the inflection point of 2.77 (95% CI: 1.64, 3.90, P < 0.0001) and - 1.18 (95% CI: - 1.46, - 0.91, P < 0.0001), respectively. The VAS score was the lowest when the degree of correction was 55.00%, with the β-value on the left and right sides of the inflection point of - 0.16 (95% CI: - 0.29, - 0.03, P = 0.0146) and 0.08 (95% CI: 0.05, 0.10, P < 0.0001), respectively. Stratified analysis showed that the BMI affected the Tinetti assessment score (β = - 0.14, 95% CI: - 0.24, - 0.04, P = 0.0071). According to the smooth-curve fitting results, when the BMI was > 28, the Tinetti assessment score showed a negative trend.
conclusionThe degree of lower-limb mechanical axis correction correlated with the functional status of the knee joint after MOW HTO. When the ratio of the medial tibial plateau width to the total tibial plateau width was approximately 55%, the post-MOW HTO outcomes were optimized and the patients experienced the highest satisfaction. In addition, very high BMI was not conducive for the postoperative recovery of the knee joint function. LEVEL OF EVIDENCE: III Case-control study/Retrospective comparative study.
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