Evidence map›Paper›PMID 35562718›Full record

ArticleBMC ophthalmology2022

The influence of congenital and developmental cataract surgery on the ocular surface in a six-month follow-up prospective clinical study.

Xiaolei Lin, Hongzhe Li, Xiyue Zhou, Xin Liu, Fan Fan, Tianke Yang, Yi Luo

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaolei Lin *Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Hongzhe Li *Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Xiyue ZhouEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Xin LiuEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Fan FanEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Tianke YangEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Yi LuoEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China. luoyi@fudan.edu.cn.
Fudan University · CNEye & ENT Hospital of Fudan University · CN

Funding

National Natural Science Foundation of China 81870645National Natural Youth Fund of China 81900839
6 · The paper itself

Abstract

backgroundThe purpose of this study was to identify changes in tear film function and meibomian gland function in children after congenital/developmental cataract surgery.

methodsThis study enrolled 16 eyes of 16 congenital/developmental cataract patients (mean age: 8.05 ± 1.43 years) who underwent cataract surgery and 16 eyes of 16 normal volunteers (mean age: 8.31 ± 2.18 years). Clinical assessments were conducted preoperatively and at 1 week, 1, 3 and 6 months postoperatively. Symptom questionnaires, non-invasive tear film break-up time, tear meniscus height, corneal fluorescein staining, lid margin abnormality, meibomian gland expressibility, and meibography were assessed.

resultsThe ocular symptom score was significantly higher in congenital/developmental cataract patients compared to normal controls during the 5 visits (P = 0.009). And the average non-invasive tear film break-up time was significantly lower in congenital/developmental cataract patients compared to normal controls (P = 0.017). The first non-invasive tear film break-up time and average non-invasive tear film break-up time were lowest at 1 month postoperatively compared to baseline levels (P = 0.008 and P = 0.012, respectively). The lid margin score of the upper eyelid was significantly higher in congenital/developmental cataract patients compared to normal controls at 1 week postoperatively (P = 0.027). The meibum expressibility score decreased significantly during the 5 visits (P = 0.024). No significant difference was observed in meibomian gland tortuosity, meibomian gland width, meibomian gland area and meibomian gland length between the congenital/developmental group and normal controls preoperatively and at 6 months postoperatively (P > 0.05).

conclusionTear film stability and meibomian gland function are worsened transiently after congenital/developmental cataract surgery without accompanying meibomian gland morphological changes.

Indexed as

CataractDry Eye SyndromesEyelid DiseasesChildFollow-Up StudiesHumansMeibomian GlandsProspective StudiesTearsCongenital/developmental cataract surgeryDry eyeMeibomian gland functionMeibomian gland morphologyTear film stability

Identifiers

PMID35562718
PMCPMC9107251
OpenAlexW4280559053

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.