Evidence map›Paper›PMID 35562598›Full record

ArticleWorld journal of urology2022

Alternative- and focal therapy trends for prostate cancer: a total population analysis of in-patient treatments in Germany from 2006 to 2019.

Luka Flegar, Aristeidis Zacharis, Cem Aksoy, Hendrik Heers, Marcus Derigs, Nicole Eisenmenger, Angelika Borkowetz, Christer Groeben, Johannes Huber

Abstract read
In one paragraph

Article in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  5. Review
  6. Article
  7. Adoption of Lutetium-European journal of nuclear medicine and molecular imaging · 2023
    Article
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luka FlegarDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany. luka.flegar@uk-gm.de.ORCID http://orcid.org/0000-0002-1477-9161
Aristeidis ZacharisDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.
Cem AksoyDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.
Hendrik HeersDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.
Marcus DerigsDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.
Nicole EisenmengerReimbursement Institute, Hürth, Germany.
Angelika BorkowetzDepartment of Urology, TU Dresden, Dresden, Germany.
Christer GroebenDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.
Johannes HuberDepartment of Urology, Philipps-University Marburg, Baldingerstr., 35043, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFocal therapy (FT) offers an alternative approach for prostate cancer (PCa) treatment in selected patients. However, little is known on its actual establishment in health care reality. PATIENTS AND

methodsWe defined FT as high-intensity focused ultrasound (HIFU), hyperthermia ablation, cryotherapy, transurethral ultrasound ablation (TULSA) or vascular-targeted photodynamic therapy (VTP) TOOKAD

resultsWe identified 23,677 cases of FT from 2006 to 2019. Considering all PCa cases with surgery, radiotherapy or FT, the share of FT was stable at 4%. The annual caseload of FT increased to a maximum of 2653 cases in 2008 (p < 0.001) and then decreased to 1182 cases in 2014 (p < 0.001). Since 2015, the cases of FT remained on a plateau around 1400 cases per year. The share of HIFU was stable at 92-96% from 2006 to 2017 and decreased thereafter to 75% in 2019 (p = 0.015). In 2019, VTP-TOOKAD

conclusionThe FT development in Germany followed the Gartner hype cycle. While HIFU treatment is the most commonly performed FT, the share of newer FT modalities such as VTP-TOOKAD

Indexed as

High-Intensity Focused Ultrasound AblationPhotochemotherapyProstatic NeoplasmsGermanyHumansMaleQuality of LifeTreatment OutcomeFocal therapyHIFUPopulation-basedProstate cancerTOOKAD®TrendsTULSA

Identifiers

PMID35562598
PMCPMC9236973

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.