Evidence map›Paper›PMID 35562423›Full record

ReviewNature protocols2022

A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide in cells and animal tissues.

Kaede Hoshi, Marco S Messina, Jun Ohata, Clive Yik-Sham Chung, Christopher J Chang

Open access · greenAbstract readReview
In one paragraph

Review in Nature protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. A histochemical approach to activity-based copper sensing reveals cuproplasia-dependent vulnerabilities in cancer.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Kaede Hoshi *Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.
Marco S Messina *Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0003-2827-118X
Jun OhataDepartment of Chemistry, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-3614-7472
Clive Yik-Sham ChungDepartment of Chemistry, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0003-1382-719X
Christopher J ChangDepartment of Chemistry, University of California, Berkeley, Berkeley, CA, USA. chrischang@berkeley.edu.ORCID http://orcid.org/0000-0001-5732-9497
University of California, Berkeley · USNorth Carolina State University · USUniversity of Hong Kong · HK

Funding

Molecular Imaging Probes To Study Redox BiologyR01GM079465 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2006 to 2026
$7.8M
Chemical Probes to Study Formaldehyde BiologyR01ES028096 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2017 to 2026
$4.1M
Chemical Probes to Study Methionine Redox BiologyR01GM139245 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2020 to 2026
$2.9M
An Activity-Based Biomolecule Labeling Platform for the Imaging of Cells and Tissues Under Oxidative StressK99GM143573 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MESSINA, MARCO · 2021 to 2022
$160k
NIEHS NIH HHS R01 ES028096NIGMS NIH HHS K99 GM143573NIGMS NIH HHS R01 GM079465NIGMS NIH HHS R01 GM139245
6 · The paper itself

Abstract

Hydrogen peroxide (H

Indexed as

Hydrogen PeroxideSignal TransductionAnimalsFluorescent DyesMiceOxidation-ReductionStaining and LabelingFluorescent DyesHydrogen Peroxide

Identifiers

PMID35562423
PMCPMC10233361
OpenAlexW4280572101

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.