Evidence map›Paper›PMID 35562119›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

Cutting Edge: T Cell Responses to B.1.1.529 (Omicron) SARS-CoV-2 Variant Induced by COVID-19 Infection and/or mRNA Vaccination Are Largely Preserved.

Mladen Jergović, Christopher P Coplen, Jennifer L Uhrlaub, Shawn C Beitel, Jefferey L Burgess, Karen Lutrick, Katherine D Ellingson, Makiko Watanabe, Janko Nikolich-Žugich

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mladen JergovićDepartment of Immunobiology, University of Arizona College of Medicine-Tucson, Tucson, AZ.
Christopher P CoplenDepartment of Immunobiology, University of Arizona College of Medicine-Tucson, Tucson, AZ.
Jennifer L UhrlaubDepartment of Immunobiology, University of Arizona College of Medicine-Tucson, Tucson, AZ.
Shawn C BeitelMel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ.
Jefferey L BurgessMel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ.ORCID 0000-0003-2362-9509
Karen LutrickDepartment of Family and Community Medicine, University of Arizona College of Medicine-Tucson, Tucson, AZ.
Katherine D EllingsonMel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ.ORCID 0000-0001-7624-312X
Makiko WatanabeDepartment of Immunobiology, University of Arizona College of Medicine-Tucson, Tucson, AZ.ORCID 0000-0002-6694-3066
Janko Nikolich-ŽugichDepartment of Immunobiology, University of Arizona College of Medicine-Tucson, Tucson, AZ; nikolich@arizona.edu.
University of Arizona · US

Funding

T Cell Homeostasis and Function in Immune SenescenceR37AG020719 · NIA · UNIVERSITY OF ARIZONA · PI JANKO Z. NIKOLICH · 2018 to 2026
$4.2M
NIA NIH HHS R37 AG020719
6 · The paper itself

Abstract

Several studies have demonstrated that the SARS-CoV-2 variant-of-concern B.1.1.529 (Omicron) exhibits a high degree of escape from Ab neutralization. Therefore, it is critical to determine how well the second line of adaptive immunity, T cell memory, performs against Omicron. To this purpose, we analyzed a human cohort (

Indexed as

COVID-19COVID-19 VaccinesmRNA VaccinesSARS-CoV-2T-LymphocytesAntibodies, ViralHumansImmunity, CellularInterleukin-2VaccinationVaccines, SyntheticAntibodies, ViralCOVID-19 VaccinesInterleukin-2mRNA VaccinesVaccines, Synthetic

Identifiers

PMID35562119
PMCPMC9179171
OpenAlexW4280652613

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.