Evidence map›Paper›PMID 35561747›Full record

ReviewFEMS yeast research2022

Post-transcriptional regulation during stress.

Mariana Hernández-Elvira, Per Sunnerhagen

Open access · hybridAbstract readReview
In one paragraph

Review in FEMS yeast research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Regulation Ratio: A Singular Multi-Omic Measurement of Gene Regulatory Mechanisms.Computational and structural biotechnology journal · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. A ZnCommunications biology · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Roles of P-body factors inbioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Review
  19. Temporal Expression Analysis to Unravel Gene Regulatory Dynamics by microRNAs.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mariana Hernández-ElviraDepartment of Chemistry and Molecular Biology, Lundberg Laboratory, University of Gothenburg, PO Box 462, S-405 30 Göteborg, Sweden.ORCID 0000-0003-4191-9550
Per SunnerhagenDepartment of Chemistry and Molecular Biology, Lundberg Laboratory, University of Gothenburg, PO Box 462, S-405 30 Göteborg, Sweden.ORCID 0000-0002-0967-8729
University of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To remain competitive, cells exposed to stress of varying duration, rapidity of onset, and intensity, have to balance their expenditure on growth and proliferation versus stress protection. To a large degree dependent on the time scale of stress exposure, the different levels of gene expression control: transcriptional, post-transcriptional, and post-translational, will be engaged in stress responses. The post-transcriptional level is appropriate for minute-scale responses to transient stress, and for recovery upon return to normal conditions. The turnover rate, translational activity, covalent modifications, and subcellular localisation of RNA species are regulated under stress by multiple cellular pathways. The interplay between these pathways is required to achieve the appropriate signalling intensity and prevent undue triggering of stress-activated pathways at low stress levels, avoid overshoot, and down-regulate the response in a timely fashion. As much of our understanding of post-transcriptional regulation has been gained in yeast, this review is written with a yeast bias, but attempts to generalise to other eukaryotes. It summarises aspects of how post-transcriptional events in eukaryotes mitigate short-term environmental stresses, and how different pathways interact to optimise the stress response under shifting external conditions.

Indexed as

SchizosaccharomycesSchizosaccharomyces pombe ProteinsGene Expression RegulationGene Expression Regulation, FungalSaccharomyces cerevisiaeStress, PhysiologicalSchizosaccharomyces pombe ProteinsbiologyRNASaccharomyces cerevisiaeSchizosaccharomyces pombe

Identifiers

PMID35561747
PMCPMC9246287
OpenAlexW4280585211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.