ArticleCurrent biology : CB2022
Sleep spindles track cortical learning patterns for memory consolidation.
Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Sleep EEG oscillations and synaptic plasticity in memory consolidation across NREM and REM sleep.Dialogues in clinical neuroscience · 2027Review
- Theta oscillations tag episodic memories for sleep-dependent consolidation.PLoS biology · 2026Article
- Manipulating memory processing during sleep to explore the critical duration of reactivation events.Neuropsychologia · 2025Article
- Exploring Deep Magnetoencephalography via Thalamo-Cortical Sleep Spindles.Human brain mapping · 2025Article
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- Physical activity simultaneously improves working memory and ripple-spindle coupling.Communications biology · 2025Article
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- CPAP modulation of sleep microstructure (N2-SSD and REM-AHI) as predictors of neurological recovery in ischemic stroke patients with moderate-to-severe OSA.Frontiers in neurology · 2025Article
- A visual paired associate learning (vPAL) paradigm to study memory consolidation during sleep.Journal of sleep research · 2024Article
- Oscillatory-Quality of sleep spindles links brain state with sleep regulation and function.Science advances · 2024Article
- Python/NEURON code for simulating biophysically realistic thalamocortical dynamics during sleep.Software impacts · 2024Article
- Slow-wave sleep drives sleep-dependent renormalization of synaptic AMPA receptor levels in the hypothalamus.PLoS biology · 2024Article
- Reactivating cue approached positive personality traits during sleep promotes positive self-referential processing.iScience · 2024Article
- Modulating social learning-induced evaluation updating during human sleep.NPJ science of learning · 2024Article
- Waking Up Brain with Electrical Stimulation to Boost Memory in Sleep: A Neuroscience Exploration.Neuroscience bulletin · 2024Article
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- Memory ability and retention performance relate differentially to sleep depth and spindle type.iScience · 2023Article
- Better late than never: sleep still supports memory consolidation after prolonged periods of wakefulness.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
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Authors and funding
5 authors.
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Abstract
Memory consolidation-the transformation of labile memory traces into stable long-term representations-is facilitated by post-learning sleep. Computational and biophysical models suggest that sleep spindles may play a key mechanistic role for consolidation, igniting structural changes at cortical sites involved in prior learning. Here, we tested the resulting prediction that spindles are most pronounced over learning-related cortical areas and that the extent of this learning-spindle overlap predicts behavioral measures of memory consolidation. Using high-density scalp electroencephalography (EEG) and polysomnography (PSG) in healthy volunteers, we first identified cortical areas engaged during a temporospatial associative memory task (power decreases in the alpha/beta frequency range, 6-20 Hz). Critically, we found that participant-specific topographies (i.e., spatial distributions) of post-learning sleep spindle amplitude correlated with participant-specific learning topographies. Importantly, the extent to which spindles tracked learning patterns further predicted memory consolidation across participants. Our results provide empirical evidence for a role of post-learning sleep spindles in tracking learning networks, thereby facilitating memory consolidation.
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