Evidence map›Paper›PMID 35561291›Full record

ArticleJCO global oncology2022

Long-Term Outcomes and Safety Trends of Autologous Stem-Cell Transplantation in Non-Hodgkin Lymphoma: A Report From A Tertiary Care Center in India.

Sudhir Kumar, Atul Sharma, Raja Pramanik, Neha Pathak, Ajay Gogia, Akash Kumar, Smita Kayal, Vinod Sharma, Ranjit Kumar Sahoo, Sanjay Thulkar and 5 more

Abstract read
In one paragraph

Article in JCO global oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Autologous Stem Cell Transplantation in Adult Hodgkin Lymphoma at a Tertiary Care Center in India: Analysis of Outcomes and Prognostic Factors.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sudhir KumarDepartment of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0002-6593-175X
Atul SharmaDepartment of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0002-0372-5336
Raja PramanikDepartment of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0003-0483-6254
Neha PathakDepartment of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0003-1839-8558
Ajay GogiaDepartment of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0001-6500-1061
Akash KumarDepartment of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.
Smita KayalDepartment of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Vinod SharmaDepartment of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.
Ranjit Kumar SahooDepartment of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0002-4130-724X
Sanjay ThulkarDepartment of Radio Diagnosis, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.
M C SharmaDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Ritu GuptaDepartment of Medical Oncology, Lab Oncology Unit, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0001-5364-4086
Soumya MallickDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0003-4366-5873
Mercy ThomasDepartment of Medical Oncology, Dr BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.
Vinod RainaFortis Memorial Research Institute, Gurgaon, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePublished experience with autologous stem-cell transplantation (ASCT) in non-Hodgkin lymphoma (NHL) from the Indian subcontinent is extremely limited. Here, we describe the activity and outcomes of this treatment modality at a large tertiary care center in India. PATIENTS AND

methodsWe retrospectively analyzed adult patients with NHL who were eligible for ASCT and autografted between January 1, 2002, and December 15, 2020, at our transplant unit. Toxicities, complications, and long-term outcomes were compared between patients who underwent transplant during 2002-2012 (group A) and 2013-2020 (group B).

resultsOverall, 80 patients (group A, n = 37; group B, n = 43) underwent ASCT using peripheral blood stem cells. At a median follow-up of 57.6 months, the 5-year event-free survival (EFS) and overall survival (OS) were 43.5% and 47.6%, respectively, for all patients. More recently (group B), patients had reduced 100-day transplant-related mortality (2.3%

conclusionIt is feasible to achieve comparable short- and long-term outcomes in patients with NHL undergoing ASCT in a resource-poor country with improved supportive care and expertise of the transplant team and center.

Indexed as

Hematopoietic Stem Cell TransplantationLymphoma, Non-HodgkinAdultAntineoplastic Combined Chemotherapy ProtocolsDisease-Free SurvivalHumansRetrospective StudiesTertiary Care Centers

Identifiers

PMID35561291
PMCPMC9302266

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.