ArticleJournal of cancer policy2021
Characteristics of colorectal cancers among Alaska Native people before and after implementing programs to promote screening.
Article in Journal of cancer policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Colorectal Cancer in the American Indian and Alaska Native Community: A Holistic Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Review
- Cost of colorectal cancer screening in two tribal health organizations in Alaska.Cancer causes & control : CCC · 2025Article
- The Translational Research Program in Cancer Differences across Populations.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Addressing Colorectal Cancer Among Alaska Native Peoples: A Community and Subject Matter Expert Symposium.Gastro hep advances · 2025Article
- Clinical Outcomes from the Alaska Native Tribal Health Consortium Colorectal Cancer Control Program: 2009-2015.International journal of environmental research and public health · 2024Article
- Impact of organised colorectal cancer screening on age-specific population incidences: evidence from a quasi-experimental study in Sweden.European journal of epidemiology · 2024Article
- Elevated colorectal cancer incidence among American Indian/Alaska Native persons in Alaska compared to other populations worldwide.International journal of circumpolar health · 2023Review
- Provider- and System-Level Barriers and Facilitators to Colonoscopy and Multi-Target Stool DNA for Colorectal Cancer Screening in Rural/Remote Alaska Native Communities.International journal of environmental research and public health · 2023Article
- "Sorry for laughing, but it's scary": humor and silence in discussions of Colorectal Cancer with Urban American Indians.BMC cancer · 2023Article
- Cancer Screening Prevalence among Participants in the Southcentral Alaska Education and Research towards Health (EARTH) Study at Baseline and Follow-Up.International journal of environmental research and public health · 2023Article
- The Alaska Native Tumour Registry: fifty years of cancer surveillance data for Alaska Native people.International journal of circumpolar health · 2022Article
- Colorectal cancer statistics, 2026.CA: a cancer journal for cliniciansObservational
- Elevated Adenomatous Polyp Detection Rate Among Alaska Native and American Indian People in Interior Alaska, 2018-2022.Public health reports (Washington, D.C. : 1974)Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundAlaska Native (AN) people have the highest rates of colorectal cancer (CRC) globally. Increasing CRC screening has been effective in reducing CRC-related morbidity and mortality in other populations.
objectiveTo examine recent descriptive epidemiology and longer-term CRC trends among AN people. To determine any changes in the descriptive epidemiology of CRC among AN people concurrent with increases in screening prevalence.
methodsWe estimated age-specific CRC incidence and mortality rates 2000-2017. To examine longer-term trends in incidence and mortality 1990-2017, we conducted Joinpoint regression analyses of three-year rolling average incidence and mortality rates. We calculated descriptive statistics for two time-periods: 2000-2008, and 2009-2017. Finally, we examined five-year survival probability.
resultsCRC incidence increased over time (1990-2017) among AN people aged less than 50 years, while there were modest declines in AN people older than 50 years old since 2000. Overall, AN CRC mortality rates declined between 1990 and 2004, but have been increasing steadily since that time. Comparing 2000-2008 with 2009-2017 we observed no difference in CRC incidence and mortality, age at diagnosis, tumor size, tumor location, or stage distribution. Survival analyses indicated no change in hazard of death between 2004-2008 and 2009-2017 (HR 1.02, 95 % CI: 0.74, 1.38, P = 0.93).
conclusionsColorectal cancer prevention and control efforts across the Alaska Tribal Health System have not yet resulted in reduced mortality rates, or induced earlier stage migration. POLICY SUMMARY STATEMENT: Intensified efforts will be necessary to reduce the burden of CRC among this high-risk population. Continued and increased focus on primary and secondary prevention efforts is warranted.
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