Evidence map›Paper›PMID 35559723›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2022

Reliability of heart rate variability during stable and disrupted polysomnographic sleep.

Emma M Kerkering, Ian M Greenlund, Jeremy A Bigalke, Gianna C L Migliaccio, Carl A Smoot, Jason R Carter

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Guidelines for rigor and reproducibility of heart rate variability within human cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Improving rigor and reproducibility in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emma M KerkeringDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana.
Ian M GreenlundDepartment of Health and Human Development, Montana State University, Bozeman, Montana.
Jeremy A BigalkeDepartment of Health and Human Development, Montana State University, Bozeman, Montana.
Gianna C L MigliaccioDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana.
Carl A SmootDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana.
Jason R CarterDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, Montana.ORCID 0000-0001-7350-6537
Montana State University · US

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Tracking and Evaluation CoreU54GM115371 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI HOPKINS, SCARLETT H · 2016 to 2020
$20.9M
Alcohol and Neurovascular Control in HumansR01AA024892 · NIAAA · MONTANA STATE UNIVERSITY - BOZEMAN · PI CARTER, JASON R · 2017 to 2021
$1.8M
HHS | National Institutes of Health (NIH) P20GM103474HHS | National Institutes of Health (NIH) R01AA024892HHS | National Institutes of Health (NIH) U54GM115371NIAAA NIH HHS R01 AA024892NIGMS NIH HHS P20 GM103474NIGMS NIH HHS U54 GM115371
6 · The paper itself

Abstract

Heart rate variability (HRV) is commonly used within sleep and cardiovascular research, yet HRV reliability across various sleep stages remains equivocal. The present study examined the reliability of frequency- and time-domain HRV within stage-2 (N2), slow-wave (SWS), and rapid-eye-movement (REM) sleep during both stable and disrupted sleep. We hypothesized that high-frequency (HF) HRV would be reliable in all three sleep stages, low-frequency (LF) HRV would be reliable during N2 and SWS, and that disrupted sleep via spontaneous cortical arousals would decrease HRV reliability. Twenty-seven participants (11 men, 16 women, 26 ± 1 yr) were equipped with laboratory polysomnography for 1 night. Both frequency- and time-domain HRV were analyzed in two 5- to 10-min blocks during multiple stable and disrupted sleep cycles across N2, SWS, and REM sleep. HF HRV was highly correlated across stable N2 (

Indexed as

Autonomic Nervous SystemSleep StagesBradycardiaFemaleHeart RateHumansMaleReproducibility of ResultsSleepautonomic controlcardiovascular healthcortical arousalssleep disorders

Identifiers

PMID35559723
PMCPMC9169847
OpenAlexW4280633087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.