ArticleCerebral cortex communications2022
Stimulation of the dorsolateral prefrontal cortex modulates muscle sympathetic nerve activity and blood pressure in humans.
Article in Cerebral cortex communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Repetitive transcranial magnetic stimulation-induced severe hypotension in a patient with Parkinson's disease: a case report.Acta neurologica Belgica · 2026Article
- Oscillatory Markers of Interoceptive Attention: Beta Suppression as a Neural Signature of Heartbeat Processing.Psychophysiology · 2026Article
- Approach Motivation and Reward Sensitivity: Effects of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) to Brain Hemispheres on Effort-Related Cardiovascular Response.The European journal of neuroscience · 2026Article
- Cortical excitation does not drive changes in skin sympathetic nerve activity during single-pulse transcranial magnetic stimulation in humans.Experimental brain research · 2026Article
- Evidence of central autonomic dysfunction in orthostatic hypotension of Parkinson's disease.Parkinsonism & related disorders · 2025Article
- Effect of Brain Stimulation on Effort Is Task Dependent: Evidence From an HD-tDCS Study on Cardiovascular Responses.Psychophysiology · 2025Article
- Autonomic Imbalance in Cardiomyopathy and Heart Failure: From Neurobiology to Precision Neuromodulation.Current cardiology reports · 2025Review
- A scoping review of neuromodulation techniques for controlling blood pressure: what are the ups and downs to this approach?Bioelectronic medicine · 2025Review
- The Dorsolateral Prefrontal Cortex: A High-level Hub for Allostatic Cardiovascular Control.Current neuropharmacology · 2025Review
- Single-pulse transcranial magnetic stimulation of the dorsolateral prefrontal cortex does not directly affect muscle sympathetic nerve activity in humans.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Article
- Non-additive effects of electrical stimulation of the dorsolateral prefrontal cortex and the vestibular system on muscle sympathetic nerve activity in humans.Experimental brain research · 2024Article
- Neuroimaging-based evidence for sympathetic correlation between brain activity and peripheral vasomotion during pain anticipation.Scientific reports · 2024Article
- Differential control of sympathetic outflow to muscle and skin during physical and cognitive stressors.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024Article
- Top-down control of vestibular inputs by the dorsolateral prefrontal cortex.Experimental brain research · 2023Article
- Home-Based Dynamics of Sleepiness-Related Conditions Starting at Biological Evening and Later (Beyond Working).International journal of environmental research and public health · 2023Article
- Neurogenic Background for Emotional Stress-Associated Hypertension.Current hypertension reports · 2023Review
- The role of the dorsolateral prefrontal cortex in control of skin sympathetic nerve activity in humans.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Chronic Pain-Associated Cardiovascular Disease: The Role of Sympathetic Nerve Activity.International journal of molecular sciences · 2023Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Muscle sympathetic nerve activity (MSNA) controls the diameter of arterioles in skeletalmuscle, contributing importantly to the beat-to-beat regulation of blood pressure (BP). Although brain imaging studies have shown that bursts of MSNA originate in the rostral ventrolateral medulla, other subcortical and cortical structures-including the dorsolateral prefrontal cortex (dlPFC)-contribute. Hypothesis: We tested the hypothesis that MSNA and BP could be modulated by stimulating the dlPFC. Method: dlPFC. In 22 individuals MSNA was recorded via microelectrodes inserted into the common peroneal nerve, together with continuous BP, electrocardiographic, and respiration.Stimulation of the right ( Results: Sinusoidal stimulation of either dlPFC caused cyclicmodulation of MSNA, BP and heart rate, and a significant increase in BP. Conclusion: We have shown, for the first time, that tcACS of the dlPFC in awake humans causes partial entrainment of MSNA, heart rate and BP, arguing for an important role of this higher-level cortical area in the control of cardiovascular function.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.