Evidence map›Paper›PMID 35559249›Full record

ArticleFrontiers in pharmacology2022

Emil Kolev, Lilyana Mircheva, Michael R Edwards, Sebastian L Johnston, Krassimir Kalinov, Rainer Stange, Giuseppe Gancitano, Wim Vanden Berghe, Samo Kreft

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Critical analysis of Echinacea preparations marketed in Germany.Naunyn-Schmiedeberg's archives of pharmacology · 2025
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  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Natural Ingredients to Improve Immunity.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Microorganisms · 2022
    Review
  14. Frontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 5 countries.

Emil KolevClinical Research Center DCC Convex Ltd., Sofia, Bulgaria.
Lilyana MirchevaClinical Research Center DCC Convex Ltd., Sofia, Bulgaria.
Michael R EdwardsVirtus Respiratory Research Limited, London Bioscience Innovation Centre, London, United Kingdom.
Sebastian L JohnstonVirtus Respiratory Research Limited, London Bioscience Innovation Centre, London, United Kingdom.
Krassimir KalinovMedistat Ltd. Statistical Services, Sofia, Bulgaria.
Rainer StangeCharité-Universitätsmedizin Berlin, Immanuel Hospital Berlin, Berlin, Germany.
Giuseppe Gancitano1st "Tuscania" Paratrooper Regiment Carabinieri, Italian Ministry of Defence, Livorno, Italy.
Wim Vanden BergheLaboratory of Protein Chemistry, Proteomics and Epigenetic Signaling (PPES) and Integrated Personalized and Precision Oncology Network (IPPON), Department of Biomedical Sciences, University of Antwerp (UA), Antwerp, Belgium.
Samo KreftFaculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia.
Imperial College London · GBImmanuel Krankenhaus · DEMinistry of Defence · ITUniversity of Antwerp · BEUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 vaccination is effective in preventing severe Covid-19, but efficacy in reducing viral load and transmission wanes over time. In addition, the emergence of novel SARS-CoV-2 variants increases the threat of uncontrolled dissemination and additional antiviral therapies are urgently needed for effective containment. In previous

Indexed as

antiviralCOVID-19Echinacea purpureaethanolic extractpreventionrandomized clinical trialSARS-CoV-2

Identifiers

PMID35559249
PMCPMC9087554
OpenAlexW4226323479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.