Evidence map›Paper›PMID 35559217›Full record

ArticleFrontiers in chemistry2022

Spontaneous Water Radical Cation Oxidation at Double Bonds in Microdroplets.

Lingqi Qiu, Nicolás M Morato, Kai-Hung Huang, R Graham Cooks

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Observation of the Charge Resonance Band of Hemibonded (HThe journal of physical chemistry letters · 2026
    Article
  3. Article
  4. Recent Advances in Reactive Microdroplets for Clean Water and Energy.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  5. Accelerated Synthesis of Pyrazoles Mediated by Water Microdroplets.ACS sustainable chemistry & engineering · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Direct electrochemical evidence suggests that aqueous microdroplets spontaneously produce hydrogen peroxide.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Efficient catalyst-free NNature communications · 2024
    Article
  11. Silica particles convert thiol-containing molecules to disulfides.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Re-Imagining Drug Discovery using Mass Spectrometry.Israel journal of chemistry · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Aqueous microdroplets enable abiotic synthesis and chain extension of unique peptide isomers from free amino acids.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lingqi QiuDepartment of Chemistry and Center for Analytical Instrumentation Development, Purdue University, West Lafayette, IN, United States.
Nicolás M MoratoDepartment of Chemistry and Center for Analytical Instrumentation Development, Purdue University, West Lafayette, IN, United States.
Kai-Hung HuangDepartment of Chemistry and Center for Analytical Instrumentation Development, Purdue University, West Lafayette, IN, United States.
R Graham CooksDepartment of Chemistry and Center for Analytical Instrumentation Development, Purdue University, West Lafayette, IN, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous oxidation of compounds containing diverse X=Y moieties (e.g., sulfonamides, ketones, esters, sulfones) occurs readily in organic-solvent microdroplets. This surprising phenomenon is proposed to be driven by the generation of an intermediate species [M+H

Indexed as

fragmentation mechanismhigh-throughput screeninginterfacial reactionionizationion thermochemistrymass spectrometryreaction accelerationsolvation

Identifiers

PMID35559217
PMCPMC9086510

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.