Evidence map›Paper›PMID 35559166›Full record

ArticleACS omega2022

Identification of a Trm732 Motif Required for 2'-

Holly M Funk, Daisy J DiVita, Hannah E Sizemore, Kendal Wehrle, Catherine L W Miller, Morgan E Fraley, Alex K Mullins, Adrian R Guy, Eric M Phizicky, Michael P Guy

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. The life and times of a tRNA.RNA (New York, N.Y.) · 2023
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Holly M FunkDepartment of Chemistry & Biochemistry, Northern Kentucky University, Highland Heights, Kentucky 41076, United States.
Daisy J DiVitaDepartment of Chemistry & Biochemistry, Northern Kentucky University, Highland Heights, Kentucky 41076, United States.
Hannah E SizemoreDepartment of Chemistry & Biochemistry, Northern Kentucky University, Highland Heights, Kentucky 41076, United States.
Kendal WehrleDepartment of Chemistry & Biochemistry, Northern Kentucky University, Highland Heights, Kentucky 41076, United States.
Catherine L W MillerDepartment of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, New York 14642, United States.
Morgan E FraleyDepartment of Chemistry & Biochemistry, Northern Kentucky University, Highland Heights, Kentucky 41076, United States.
Alex K MullinsDepartment of Chemistry & Biochemistry, Northern Kentucky University, Highland Heights, Kentucky 41076, United States.
Adrian R GuyDepartment of Chemistry & Biochemistry, Northern Kentucky University, Highland Heights, Kentucky 41076, United States.
Eric M PhizickyDepartment of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, New York 14642, United States.
Michael P GuyDepartment of Chemistry & Biochemistry, Northern Kentucky University, Highland Heights, Kentucky 41076, United States.ORCID https://orcid.org/0000-0002-4443-5263
Northern Kentucky University · USUniversity of Rochester · US

Funding

TRNA SPLICINGR01GM052347 · NIGMS · UNIVERSITY OF ROCHESTER · PI Eric M. Phizicky · 1995 to 2026
$9.6M
Identification of Novel Human tRNA Modification GenesR15GM128050 · NIGMS · NORTHERN KENTUCKY UNIVERSITY · PI Michael P. Guy · 2018 to 2026
$1.3M
NIGMS NIH HHS R01 GM052347NIGMS NIH HHS R15 GM128050
6 · The paper itself

Abstract

Posttranscriptional tRNA modifications are essential for proper gene expression, and defects in the enzymes that perform tRNA modifications are associated with numerous human disorders. Throughout eukaryotes, 2'-

Identifiers

PMID35559166
PMCPMC9088939
OpenAlexW4224214070

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.