Evidence map›Paper›PMID 35558959›Full record

ArticleRSC advances2018

Chemo-photothermal effects of doxorubicin/silica-carbon hollow spheres on liver cancer.

Ying-Chi Chen, Wen-Tai Chiu, Chin Chang, Ping-Ching Wu, Ting-Yuan Tu, Hong-Ping Lin, Hsien-Chang Chang

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Silica-Based Nanoframeworks Involved Hepatocellular Carcinoma Theranostic.Frontiers in bioengineering and biotechnology · 2021
    Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying-Chi ChenDepartment of Biomedical Engineering, National Cheng Kung University Tainan Taiwan wtchiu@mail.ncku.edu.tw hcchang@mail.ncku.edu.tw.ORCID https://orcid.org/0000-0003-3711-0329
Wen-Tai ChiuDepartment of Biomedical Engineering, National Cheng Kung University Tainan Taiwan wtchiu@mail.ncku.edu.tw hcchang@mail.ncku.edu.tw.
Chin ChangDepartment of Chemistry, National Cheng Kung University Tainan Taiwan hplin@mail.ncku.edu.tw.
Ping-Ching WuDepartment of Biomedical Engineering, National Cheng Kung University Tainan Taiwan wtchiu@mail.ncku.edu.tw hcchang@mail.ncku.edu.tw.
Ting-Yuan TuDepartment of Biomedical Engineering, National Cheng Kung University Tainan Taiwan wtchiu@mail.ncku.edu.tw hcchang@mail.ncku.edu.tw.
Hong-Ping LinDepartment of Chemistry, National Cheng Kung University Tainan Taiwan hplin@mail.ncku.edu.tw.ORCID https://orcid.org/0000-0001-9021-3146
Hsien-Chang ChangDepartment of Biomedical Engineering, National Cheng Kung University Tainan Taiwan wtchiu@mail.ncku.edu.tw hcchang@mail.ncku.edu.tw.ORCID https://orcid.org/0000-0001-7874-1712

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemo-photothermal therapy, which exhibits synergistic effects, is more effective than either of the treatments administered alone because of its superior ability to target and destroy cancer cells. An anti-cancer compound (doxorubicin, DOX) was embedded in silica-carbon hollow spheres (SCHSs) using heat and vacuum to integrate multi-therapeutic effects onto one platform and subsequently improve the anti-cancer efficacy. SCHSs were synthesized

Identifiers

PMID35558959
PMCPMC9089277

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.