Evidence map›Paper›PMID 35558937›Full record

ArticleRSC advances2018

Total synthesis of μ-conotoxin lt5d.

A M B Naraga, O J V Belleza, A J L Villaraza

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A M B NaragaInstitute of Chemistry, College of Science, National Science Complex, University of the Philippines Diliman Quezon City 1100 Philippines alvillaraza@up.edu.ph.ORCID https://orcid.org/0000-0002-5768-3813
O J V BellezaInstitute of Chemistry, College of Science, National Science Complex, University of the Philippines Diliman Quezon City 1100 Philippines alvillaraza@up.edu.ph.ORCID https://orcid.org/0000-0002-6383-6636
A J L VillarazaInstitute of Chemistry, College of Science, National Science Complex, University of the Philippines Diliman Quezon City 1100 Philippines alvillaraza@up.edu.ph.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The total synthesis of μ-conotoxin lt5d is presented for the first time employing two different strategies. One involves glutathione-assisted oxidation where all disulphide linkages are formed simultaneously. Another involves orthogonal protection of cysteine residues, allowing the controlled formation of disulphide linkages sequentially. Both methods achieve the same peptide.

Identifiers

PMID35558937
PMCPMC9088864

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.