ArticleFrontiers in veterinary science2022
Case Report: MRI, Clinical, and Pathological Correlates of Bromethalin Toxicosis in Three Dogs.
Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Magnetic resonance imaging pattern recognition of metabolic and neurodegenerative encephalopathies in dogs and cats.Frontiers in veterinary science · 2024Article
- An atypical presentation of anticoagulant rodenticide toxicosis in a dog.The Canadian veterinary journal = La revue veterinaire canadienne · 2023Article
- Case report: Recovery and sequential imaging of a patient with osmotic demyelination syndrome.Frontiers in veterinary science · 2023Article
- Bromethalin Exposure in Dogs and Cats: A 14-Year Retrospective Study (2010-2023) From the California Animal Health and Food Safety Laboratory System.Journal of veterinary internal medicineArticle
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bromethalin toxicosis is an increasingly common clinical presentation in dogs that may be fatal depending on the extent of intoxication. Antemortem diagnosis of bromethalin toxicosis was achieved in three dogs by demonstration of the active metabolite desmethylbromethalin in fat or serum. Magnetic resonance imaging (MRI) findings were consistent with a diffuse leukoencephalopathy with restricted diffusion and prominent involvement of the corticospinal motor tracts on T2-weighted and diffusion-weighted sequences. Imaging findings were confirmed in one non-surviving dog at necropsy. Resolution of MRI abnormalities was demonstrated in one surviving dog that was consistent with the associated resolution of clinical signs. Initial findings in these dogs support further investigation of specific MRI patterns in cases of leukoencephalopathy to aid differential diagnosis. While antemortem detection of bromethalin and its metabolites confirms exposure, quantitation may be informative as a prognostic biomarker.
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