Evidence map›Paper›PMID 35558843›Full record

ArticleRSC advances2022

Supramolecular polymer/peptide hybrid hydrogels with tunable stiffness mediated by interchain acid-amide hydrogen bonds.

Yu-Shen Liu, Rajan Deepan Chakravarthy, Abdelreheem Abdelfatah Saddik, Mohiuddin Mohammed, Hsin-Chieh Lin

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Advances in Regulating Cellular Behavior Using Micropatterns.The Yale journal of biology and medicine · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Yu-Shen LiuDepartment of Materials Science and Engineering, National Yang Ming Chiao Tung University Hsinchu 300 Taiwan hclin45@nycu.edu.tw.ORCID https://orcid.org/0000-0002-9353-732X
Rajan Deepan ChakravarthyDepartment of Materials Science and Engineering, National Yang Ming Chiao Tung University Hsinchu 300 Taiwan hclin45@nycu.edu.tw.ORCID https://orcid.org/0000-0002-5398-0992
Abdelreheem Abdelfatah SaddikDepartment of Materials Science and Engineering, National Yang Ming Chiao Tung University Hsinchu 300 Taiwan hclin45@nycu.edu.tw.ORCID https://orcid.org/0000-0001-7472-3453
Mohiuddin MohammedDepartment of Materials Science and Engineering, National Yang Ming Chiao Tung University Hsinchu 300 Taiwan hclin45@nycu.edu.tw.ORCID https://orcid.org/0000-0001-7254-0506
Hsin-Chieh LinDepartment of Materials Science and Engineering, National Yang Ming Chiao Tung University Hsinchu 300 Taiwan hclin45@nycu.edu.tw.ORCID https://orcid.org/0000-0002-3596-3224
National Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels are a class of biomaterials used in the field of tissue engineering and drug delivery. Many tissue engineering applications depend on the material properties of hydrogel scaffolds, such as mechanical stiffness, pore size, and interconnectivity. In this work, we describe the synthesis of peptide/polymer hybrid double-network (DN) hydrogels composed of supramolecular and covalent polymers. The DN hydrogels were prepared by combining the self-assembled pentafluorobenzyl diphenylalanyl aspartic acid (PFB-FFD) tripeptide for the first network and the polymeric PNIPAM-PEGDA copolymer for the second network. During this process, self-assembled peptide nanostructures are cross-linked to the polyacrylamide group in the polymer network through non-covalent interactions. The PNIPAM-PEGDA:PFB-FFD hydrogel exhibited higher mechanical stiffness (

Identifiers

PMID35558843
PMCPMC9093129
OpenAlexW4280504119

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.